DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and CG5568

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	154/532 - (28%)
Similarity:	270/532 - (50%)	Gaps:	25/532 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YDAASRTWFGPRGKDFYGPEMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQAF 71
            :|...:.|.|...:..:.|::::||:|.:.::.||....||..|...|||...:...:.::|...
  Fly    17 FDENLKIWSGGEKRSLFSPDLSIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYM 81

  Fly    72 KRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVEN 136
            ::|||.:||.||:....:|:||::..|....|.|.:.||.|:.:..::.::.||:|::||||.:.
  Fly    82 RKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDGDE 146

  Fly   137 YHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAAYVPCPKLHG-DHTAFIVCSSG 200
            :..::.....||  .:|..:.....|:|.|.::|.....:.   :.|.....| |....|:.|||
  Fly   147 FEKVQAATKGLQ--VQIVTMRNHPAGILRIQDILTTPVEMN---FRPVRLKDGTDQLLAILSSSG 206

  Fly   201 TTGMPKGVTRSHRSLLCNCKNPNTYTRDSVLLSFSP--LYWISGTIILLASLLNGCRRIITNRPY 263
            |:|:||.||.|:...:.....|    .||.::.::|  |.|.||..:.:.:.:.....||.:..:
  Fly   207 TSGLPKAVTISNSHQIIGSFLP----VDSSIIQYNPNTLDWASGITMTINAAVFSLTSIIEDCDF 267

  Fly   264 SVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMEL-KAQLQSIRVLIGAGSKVCKAVCRRMYE 327
            ....|..|:.:::::.:|::|.|:|:|    |:..|. .|.|.|::.....||.....|..::..
  Fly   268 DPANLCGLIEKYRISMVFVSSSQLAML----SNCPEFYAADLSSVKYFFYGGSNCSLEVQNKIRS 328

  Fly   328 LIGNQRFVVGYGLSEM---GGLSKNVGGPVGCEGKVMRNVELRVLDKLKMPLGINEVGIIYARLR 389
            .:.|:.....|.|:|:   |.|:.|........|:.:|.::::::::|....|.|.||.|.....
  Fly   329 RLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVNELGEAQGPNVVGEICFNNG 393

  Fly   390 FKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFIL 454
            .||.|||:|||.|::...|:. ||.|||:||:|.:|||:|..|..|:.|:.....||.:||..|.
  Fly   394 QKWPGYYKNPEETKKMQDSEN-WFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIA 457

  Fly   455 RLPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLSGAY-HIRGGVYFID 518
            .:|.|.|||||||.|.|..:..|.:||:   .:|.:|.|..:...|...:...: .:.||...:|
  Fly   458 EMPNVVEACVFGIWDPVYGDKAAASVVK---KQGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVD 519

  Fly   519 SLPKTPNDKLQR 530
            .:.::.|.|..|
  Fly   520 HIIQSGNRKANR 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	151/514 (29%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	146/498 (29%)
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	151/514 (29%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	144/491 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	8	7.860