DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and Acsm1

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001101972.2	Gene:	Acsm1 / 361638	RGDID:	1306813	Length:	577	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	112/509 - (22%)
Similarity:	210/509 - (41%)	Gaps:	47/509 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GQELTGA--QLAQQSARIAQAFKR-LGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEF 113
            |.|:..:  :|...|.|.|..|:: .||:.||.:.:..........|.:..:..|:...|...:.
  Rat    81 GDEIKWSFRELRDLSRRAANVFEQTCGLQHGDRLALILPRVPEWWLVTVGCIRTGVIFIPGTAQM 145

  Fly   114 TEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQN-PAKIYLVNGKLEGVLDISEMLNDEDSIT 177
            ..:.:.|...:::.|.|.........:::|..:... ..||.:.:...||.|:...:|.     :
  Rat   146 KAKDILYRIQMSQAKAIVTTDSLVPEVESVASECPGLKTKIVVSDHNHEGWLNFRTLLR-----S 205

  Fly   178 AAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSH----RSLLCNCKNPNTYTRDSVLLSFSPLY 238
            |:....|.|........|..:|||||.||....:.    ||.:.:|:.........|:...|...
  Rat   206 ASPDHTCVKSKMKDPMVIFFTSGTTGYPKMAKHNQGLAFRSSVPSCRKFLKLKTSDVIWCMSDPG 270

  Fly   239 WISGTI-ILLASLLNGCRRIITNRP-YSVEYLLQLVARHKVTFLFLASHQI--ALLSKHDSDVME 299
            ||..|: .||.....|....:.|.| :..:.:::.:.::.:| ..||:..:  .:|.|:.|::
  Rat   271 WILATVGCLLEPWTAGATVFVHNLPQFDPKVIVETLFKYPIT-QCLAAPAVYRMVLQKNISNL-- 332

  Fly   300 LKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMG---GLSKNVGGPVGCEGKVM 361
               :..::......|..:......:..:..|.....| ||.||.|   .:.:.:....|..||.:
  Rat   333 ---RFPTLEHCATGGESLLPEEYEQWKQRTGLSIHEV-YGQSETGITCAIFREMKVKRGSIGKAI 393

  Fly   362 RNVELRVLDKLKMPLGINEVGIIYARLRFK-------WAGYYRNPEATRRALSSDGMWFRTGDIG 419
            ...:::::|:....|..|..|  |..:|.|       :.||..:||.|......|  ::.:||..
  Rat   394 LPFDIQIIDEKGNILPPNTEG--YIGIRIKPTRPLGLFVGYENSPEKTSEVECGD--FYNSGDRA 454

  Fly   420 YLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDAVSTNLTACAVVRTK 484
            .:|.:||::...|..||...:.::|.|.::|..::..|.|||:.|...||.....:....:|...
  Rat   455 TIDEDGYIWFLGRSDDVINASGYRIGPTEVENALVEHPAVSESAVVSSPDKDRGEVVKAFIVLNP 519

  Fly   485 ---SPEGERLTADHIRNIVEH--HLSGAYHIRGGVYFIDSLPKTPNDKLQRRKV 533
               |.:.|:|    |:.:.||  .::..|.....|.|:..||||...|::|:::
  Rat   520 EFLSHDQEQL----IKELQEHVKSVTAPYKYPRKVEFVSELPKTITGKIKRKEL 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	112/509 (22%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	111/503 (22%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	112/509 (22%)
Acsm1	NP_001101972.2	Acs	46..570	CDD:223442	112/509 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010