DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and Acsm5

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001014184.3	Gene:	Acsm5 / 361637	RGDID:	1309578	Length:	578	Species:	Rattus norvegicus

Alignment Length:	511	Identity:	121/511 - (23%)
Similarity:	214/511 - (41%)	Gaps:	50/511 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 TGQEL--TGAQLAQQSARIAQAFK-RLGLRRGD--VVGISANNSTYLTSVIIAALLRGIPINPLH 110
            :|.|:  |..:|.:||.:.|...: ..||:.||  ::.:......:||  |:|.:..|:.:.|..
  Rat    83 SGTEVKWTFEELGKQSRKAANILEGACGLKPGDRLMLVLPRLPEWWLT--IVACMRTGVVMIPGI 145

  Fly   111 PEFTEETVKYMYDITEPK-VIFCDVENYHI--IKTVNGKLQNPAKIYLVNGKLEGVLDISEMLND 172
            .:.|::.:||.......| :|..|....|:  |......||  :::.:.:....|.::..|:|.
  Rat   146 SQLTQKDLKYRLQAARVKSIITSDALAPHVDAISADCPSLQ--SRLLVSDTSRPGWINFRELLR- 207

  Fly   173 EDSITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRS----LLCNCKNPNTYTRDSVLLS 233
                .|:....|.:.....:..|..:|||||.||.|..|..|    .:.:.:.....|...:..:
  Rat   208 ----VASPEHNCLRTRSGDSMAIYFTSGTTGTPKMVEHSQCSYGLGFVASGRRLMALTESDIFWN 268

  Fly   234 FSPLYWISGTIILLASLLNGCRRIITNRP-YSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDV 297
            .:...|:.....|.::..||....:...| ...:.:|..:.|..:|.:........||.:.|.
  Rat   269 TTDTGWVKAAWTLFSAWANGACVFVHELPQVDAQTILNTLCRFPITTICCVPTLFRLLVQEDL-- 331

  Fly   298 MELKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNVGGPV---GCEGK 359
              .:.:.|.:|..: ||.:...:..|..::.........|||.||...:..|..|..   |..||
  Rat   332 --TRYKFQCLRHCL-AGGEALNSDVRDKWKNQTGLEIHEGYGQSETVLICGNFRGSTIKSGSMGK 393

  Fly   360 VMRNVELRVLDKLKMPLGINEVGIIYARLR-------FKWAGYYRNPEATRRALSSDGMWFRTGD 417
            .....:::::|:....|...:.|.|..|::       |..  |..|||.|  |.|..|.::.|||
  Rat   394 ASPPYDVQIVDEEGNVLPPGKEGNIAIRIKPTRPFCLFNC--YLDNPEKT--AASEQGDFYITGD 454

  Fly   418 IGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDAVSTNLTACAVVR 482
            ..::|.:||.:...|:.||...::::|.|.::|..:...|.|.|:.|...||.:...:....:|.
  Rat   455 RAHMDEDGYFWFVGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVL 519

  Fly   483 TK---SPEGERLTADHIRNIVEH--HLSGAYHIRGGVYFIDSLPKTPNDKLQRRKV 533
            :.   |.:.|.||    |.:.||  .::..|.....|.||..||||.:.|:.|.|:
  Rat   520 SPAYVSHDPEALT----RELQEHVKTVTAPYKYPRKVAFISELPKTVSGKILRSKL 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	121/511 (24%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	119/505 (24%)
Acsm5	NP_001014184.3	AFD_class_I	48..576	CDD:418409	121/511 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010