Protein Alignment CG17999 and hll

DIOPT Version :9

• Sequence 1: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 138/646 - (21%)
• Similarity: 230/646 - (35%)
• Gaps: 177/646 - (27%)

  Fly     2 SCEVHYDAASRTWFGP-RGKDFYGPEMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSA 65
            |||.:.|..:..|..| .|.|.: ..:|.||...||                         :|:|
  Fly    45 SCEKYSDLPALVWETPGSGNDGW-TTLTFGEYQERV-------------------------EQAA 83

  Fly    66 RIAQAFKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKV- 129
            .:..:   :|:.....|||.|.|..........||..|..:..::|..:.|.|.::....|..|
  Fly    84 LMLLS---VGVEERSSVGILAFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGESSVC 145

  Fly   130 IFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLD-------------------ISEMLNDEDS 175
            :..|.:....::.:..:|.....:..::|..|..:|                   :.|.|...:|
  Fly   146 VVDDAQQMAKLRAIKERLPRLKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKEELLARES 210

  Fly   176 ITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSLLCNCKNPNTYTRD-----SVLLSFS 235
                      ::..:..|.::.:|||.||||.|..||.:|:.:.|:...:.:|     ...:|:.
  Fly   211 ----------RIRANECAMLIFTSGTVGMPKAVMLSHDNLVFDTKSAAAHMQDIQVGKESFVSYL 265

  Fly   236 PLYWISGTII-------------------LLASLLNGCRRIITNRPYSV--------EYLLQLVA 273
            ||..::..|.                   |..:|:...|:....:.:.|        |.|:...|
  Fly   266 PLSHVAAQIFDVFLGLSHAGCVTFADKDALKGTLIKTFRKARPTKMFGVPRVFEKLQERLVAAEA 330

  Fly   274 RHKVTFLFLASHQIALLSKHDSDVMELKAQ--------------LQSIRVLIGAGSKVCKAVCRR 324
            :.:.....|.:...|.:::|.:.:|..|:.              ::.||.:||..:      ||.
  Fly   331 KARPYSRLLLARARAAVAEHQTTLMAGKSPSIYGNAKYWLACRVVKPIREMIGVDN------CRV 389

  Fly   325 MY--------ELIGNQRFVVG--------YGLSEMGG-------LSKNVGGPVGCEGKVMRNVEL 366
            .:        ||   ::|.:|        ||:||..|       :|........|||..:
  Fly   390 FFTGGAPTSEEL---KQFFLGLDIALGECYGMSETSGAITLNVDISNLYSAGQACEGVTL----- 446

  Fly   367 RVLDKLKMPLGINEVGIIYARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQT 431
                |:..| ..|..|.|..|.|..:.||...|:.|...:..|| |..:||:||:|.:|.|.|..
  Fly   447 ----KIHEP-DCNGQGEILMRGRLVFMGYLGLPDKTEETVKEDG-WLHSGDLGYIDPKGNLIISG 505

  Fly   432 RDTD-VFKFNNFQIYPEQIEEFILR-LPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTAD 494
            |..: :.......|.|..|||.|.: ||.||...:.|   .....||....::||......:..|
  Fly   506 RLKELIITAGGENIPPVHIEELIKKELPCVSNVLLIG---DHRKYLTVLLSLKTKCDAKTGIPLD 567

  Fly   495 HIR----------NIVEHHLSGAYHIRGGVYFIDSLPKTPNDKLQRRKVLGLVQQLELKAE 545
            .:|          :|.|..||...:|...:       :.|||      ...|...||:.|:
  Fly   568 ALREETIEWLRDLDIHETRLSELLNIPADL-------QLPND------TAALAATLEITAK 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	129/620 (21%)
		AFD_class_I	38..529	CDD:302604	121/591 (20%)
hll	NP_609696.1	AFD_class_I	62..680	CDD:388389	132/629 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030