DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and CG18155

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	107/555 - (19%)
Similarity:	212/555 - (38%)	Gaps:	148/555 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RIAQAFKRLGLRRGDVVGISA-NNSTYLTS-------VIIAALLRGIPINPLHPEFTEETVKYMY 122
            ::..|.||||::..::.|.:| :|.|||.|       :..:..:.|....||......:.::...
  Fly    73 QLYMAAKRLGIQISNICGGAALSNVTYLCSNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQA 137

  Fly   123 DITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKL-------------EGVLDISEMLNDED 174
            ...:.|::....|...:.:.::..::: |.|.|.:..|             :.::.|..::..|:
  Fly   138 SNCKTKLLIATKEFESLAQELSQGVKS-ATIILDHSFLPTAESVSSTSMYAKQLVAIQGVIVTEN 201

  Fly   175 SITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRS----LLC----------NCKNPNTY 225
            :.....|...|       |.::.:......||.|..:||:    :.|          :|..|
  Fly   202 TFPNDFYSKAP-------AMLIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLGPTDCMLP--- 256

  Fly   226 TRDSVLLSFSPLY-------WISGTIILLASLLNGCRRIITNRPYSVEYLLQLVARHKVTFLFLA 283
                 :||.:.::       .:.|.::|.       ::...:..:|....:...::.:|| ||||
  Fly   257 -----ILSMNRMHAALAAVLSVGGNVVLQ-------QKFDGHNAWSALLGINSPSKQRVT-LFLA 308

  Fly   284 SHQI--ALLSKH------DSDVME--LKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGY 338
            ...:  .|:.::      ||.::|  :....|.||::..|.:.:..:|..|..|:.| |.....|
  Fly   309 MPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITG-QNIYEYY 372

  Fly   339 GLSEMG-----GLSKNV-----GGPV---------------GCEGKVMRNVELRVL----DKL-- 372
            |:.|.|     .|:|..     .||.               |..|..::.|..|::    |:|
  Fly   373 GMMETGLVLGHPLNKRQRDSPHNGPTAVAMANNTAPNDYRPGTLGSPLKGVTARLISNKGDELIT 437

  Fly   373 -KMPLG---------INEV-------GIIYARLRFKWAGYYRNPEAT--------------RRAL 406
             |..||         :.::       |.|...|:...:....|..|.              .:..
  Fly   438 CKNELGGSVDSGLIPVEDIGGDASLAGTIIGELQIAGSNLVSNTLANNNQEMEHKGTTNNEEQEN 502

  Fly   407 SSDGMWFRTGDI-GYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDA 470
            :.|| :|:|||| .|  ..|..|..::.:|:|....:::|..:|::.::..|.:::..|.|||:.
  Fly   503 NQDG-FFKTGDICAY--RNGNFYFLSKSSDIFTVGGYKVYGSEIKKVLISHPNINDVAVLGIPNK 564

  Fly   471 V-STNLTACAVVRTKSPEGERLTADHIRNIVEHHL 504
            : ...|....:|   ||:.: :..|.|:.....||
  Fly   565 MWGHRLGVICIV---SPDAD-IDLDAIKTYCYRHL 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	107/555 (19%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	107/555 (19%)
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	107/555 (19%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	107/555 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000