DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and Acsbg2

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_006244373.1	Gene:	Acsbg2 / 301120	RGDID:	1588580	Length:	698	Species:	Rattus norvegicus

Alignment Length:	604	Identity:	134/604 - (22%)
Similarity:	219/604 - (36%)	Gaps:	179/604 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SCEVHYDAASRTWFGP------------RGKDFYGPEMTL------GEVIMRVLQ--------IN 40
            ||.|...:......||            ||.|.......|      |||::|:.:        :.
  Rat    15 SCTVTNTSCEPAKVGPPMTQEKKAEDPDRGMDTTSAAPRLWSTHCDGEVLLRLSKHGPGHETPMT 79

  Fly    41 ADQVMQ-----------ICDTTGQE---LTGAQLAQQSARIAQAFKRLGLRRGDVVGISANNSTY 91
            ..::.|           :....|::   ||.:|......:.|::..:|||:|...|||...||..
  Rat    80 IPELFQESVERFGAYPALASKNGKKWDTLTFSQYYDVCRKAARSLIKLGLQRFHGVGILGFNSVE 144

  Fly    92 LTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQN-----PA 151
            .....:.|:|.|.....::...:.|..:|:  |.:..|....|||       :.:||.     |.
  Rat   145 WVVAALGAILAGGLCVGIYATNSAEACQYV--IKQANVNVLIVEN-------DQQLQKILSIPPD 200

  Fly   152 KIYLVNGKLEGVLDISE----MLNDEDSITAAAYVPCPKL-------HGDHTAFIVCSSGTTGMP 205
            |:..|...::..|.:.|    :.:.:|.:.....:|..:|       ..:..|.|:.:|||||.|
  Rat   201 KMETVKAIVQYRLPLMENSTNLYSWQDFMELGNAIPNIQLDRVILSQKANQCAVIIYTSGTTGSP 265

  Fly   206 KGVTRSHRSLLCNCKNPNTYT---------------RDSVLLSFSPL---------YWIS---GT 243
            |||..||.::        |:|               :...::|:.||         .||.   |.
  Rat   266 KGVMLSHDNI--------TWTAGAMAREIELIHVSGKQDTIVSYLPLSHIAAQLMDIWIPIKVGV 322

  Fly   244 IILLA--SLLNGCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQS 306
            :...|  ..|.|          ::.|.||.|   |.|: ||...::  ..|....:.|..|:..:
  Rat   323 LTFFAQPDALRG----------TLVYTLQEV---KPTY-FLGVPRV--WEKMQDTIKENVAKSSN 371

  Fly   307 IRVLIGAGSK----------------------VCKAV-------------CRRMY---------- 326
            :|....|.:|                      :.||:             |...:
  Rat   372 LRKKAFAWAKMLGLKVNTKKMLGKRDIPMNYRMAKALVFTKVRTSLGLDNCHTFFSGASPLSQDV 436

  Fly   327 -ELIGNQRFVVG--YGLSEMGG----LSKNVGGPVGCEGKVMRNVELRVLDKLKMPLGINEVGII 384
             |...:....:|  ||::|..|    ..|::...:.| |||:...:..:..:.|.  |:.|| .:
  Rat   437 SEFFLSLDIPIGEIYGMTECSGPHTVSCKSIYRVLSC-GKVLNGCKNMLYKQNKD--GVGEV-CM 497

  Fly   385 YARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDV-FKFNNFQIYPEQ 448
            :.|..|  .||....:||...|..|| |..:||||.|||..:|||..|..:| .......|:|..
  Rat   498 WGRHVF--MGYLGKEDATLEVLDEDG-WLHSGDIGRLDSHDFLYITGRIKEVLITAGGENIWPIP 559

  Fly   449 IEEFIL-RLPGVSEACVFG 466
            ||..:. ::|.:|.|.:.|
  Rat   560 IETLVKEKIPIISHAMLVG 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	126/569 (22%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	121/550 (22%)
Acsbg2	XP_006244373.1	FAA1	78..698	CDD:223953	121/541 (22%)
Acsbg2	XP_006244373.1	AFD_class_I	100..696	CDD:302604	120/519 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930