DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and Slc27a6

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001099615.1	Gene:	Slc27a6 / 291582	RGDID:	1311977	Length:	619	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	120/548 - (21%)
Similarity:	207/548 - (37%)	Gaps:	100/548 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 GQELTGAQLAQQSARIAQA-FKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTE 115
            |...|...:.::|.|:|.| .....|:|||||.:..:|......|.......|..:..|:.....
  Rat    77 GDVYTYEDVDKRSNRVAHALLNHSDLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRF 141

  Fly   116 ETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKL-EGVLDISEMLNDEDSITAA 179
            |::.:....:|||.:....:....::.:...|....:::.:...: ||::.:.|.|      :.|
  Rat   142 ESLLHCIRTSEPKAMVVGEDLLGSLEEILPSLPKHIRVWGMKDSVPEGIVSLKEKL------SLA 200

  Fly   180 AYVPCPKLHGDH-------TAFIVCSSGTTGMPKGVTRSHRSLL--------CNCKNPNTYTRDS 229
            :..|.|..|  |       |...:.:|||||:||....|...:|        ..|      |.|.
  Rat   201 SDEPVPPSH--HVTSSLKSTCLYIFTSGTTGLPKAAVISQFQVLKGSFGLWAFGC------TADD 257

  Fly   230 VLLSFSPLYWISGTIILLASLLNGCRRI----ITNRPYSVEYLLQLVARHKVTFLFLASHQIALL 290
            ::....|||..||.::    .:.||..:    :..:.:|.........::.||...........|
  Rat   258 IVYITLPLYHSSGALL----GIGGCVELGATCVLKKKFSASQFWNDCRKYNVTVFQYIGELCRYL 318

  Fly   291 SKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNVGGPVG 355
            .|......|     :..||.:..|:.:...|.|:..:..||.:....||.:|......|..|.:|
  Rat   319 CKQPQREGE-----KDHRVRLAVGNGMSSDVWRQFLDRFGNIKMCEFYGATEGNICFMNHTGKIG 378

  Fly   356 CEGKV------MRNVELRVLDKLK-MPL----------GINEVGIIYARLRFK--WAGYYRNPEA 401
            ..|:|      :.:.||...|..| .||          ...|.|::.:|:..|  :.||..:.:.
  Rat   379 SVGRVNFFYNLLFSFELIKYDFQKDEPLRNEQGWCYCVRKGEPGLLVSRVNKKNPFFGYTGSYKQ 443

  Fly   402 TRRALSSD-----GMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSE 461
            |:..|..|     .::|.|||:.:.|.|.:||...|..|.|::....:...::...:.||..:.|
  Rat   444 TKSKLLFDVFKKGDVYFNTGDLMFQDHENFLYFWDRIGDTFRWKGENVATTEVANVLGRLDFIQE 508

  Fly   462 ACVFGIP---------------------------DAVSTNLTACAVVRTKSPEGERLTADHIR-- 497
            |.|:|:|                           |.|.|:|.|.|..|....:.:..|....:
  Rat   509 ANVYGVPVPGYEGKAGMTSIILKPNKSLDLEKMYDQVVTSLPAYACPRFLRIQDKMETTGTFKLK 573

  Fly   498 --NIVEHHLSGAYHIRGGVYFIDSLPKT 523
              .:||...: ...|...:||:|:|.|:
  Rat   574 KLQLVEEGFN-PLKIADPLYFMDNLKKS 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	120/548 (22%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	120/548 (22%)
Slc27a6	NP_001099615.1	PRK08279	58..612	CDD:236217	120/548 (22%)
Slc27a6	NP_001099615.1	AFD_class_I	77..609	CDD:302604	120/548 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343020
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930