Protein Alignment CG17999 and mec-18

DIOPT Version :10

• Sequence 1: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_508731.3
• Gene: mec-18 / 180701
• WormBaseID: WBGene00003179
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 453
• Identity: 109/453 - (24%)
• Similarity: 202/453 - (44%)
• Gaps: 73/453 - (16%)

  Fly   101 LRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLD 165
            |..|.:.|:.||       .:.|:|.|            :..|:|:.:.      :||.:|
 Worm   184 LAKINLTPVLPE-------DIADLTSP------------VSEVSGQSKE------LNGDVE---- 219

  Fly   166 ISEMLNDEDSITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSLLCNCKNPN------T 224
             |.:::.|:..|     |..::.|.:...|:.:|||||:.|....|||||:.|.:..:      .
 Worm   220 -SSVVDSEEVQT-----PIQQVSGQNPLLILFTSGTTGLAKAAELSHRSLIINIQQISLPLYGPV 278

  Fly   225 YTRDSVLLSFSPLYWISGTIILLASLLNGCRRIITNRPYSVEYLLQLVARHKVTFLFLAS---HQ 286
            .|::..||..| :..|.|.:....:|:||....:.:: .|....::.:..:::..:.:..   |.
 Worm   279 QTKERFLLPLS-IAHIYGIVSAYYALINGASLYLISK-QSNRLFMETLVNNQINVMHITPAIVHW 341

  Fly   287 IALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLS---- 347
            :|.    |:.|.:.|.  .::|.::.||:.:.......|...:..:.|...:|::|:||:.
 Worm   342 MAT----DAIVDDYKT--PNLRSVLCAGAPIDSNSAAAMKSRLNIKDFRQSFGMTELGGICTMSP 400

  Fly   348 ------KNVGGPV-GCEGKVMRNVELRVLDKLKMPLGINEVGIIYARLRFKWAGYYRNPEATRRA 405
                  ::||.|: |...||: |.|.:.|...:.|..|..:|...:..      ||:||:||...
 Worm   401 YLDEKIESVGNPLPGMLFKVV-NWETKQLCLPRQPGQIIVLGPQVSPC------YYKNPKATSEL 458

  Fly   406 LSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEACVFGIPDA 470
            ..:.| :.:|||.|:.|..|.:|:..|..|:.|.....|.|.::|..:....|:.:..|.|..|.
 Worm   459 FDATG-FVKTGDAGFYDEVGRIYVLDRIKDIIKCKGTMICPSEVELVLRAHAGIDDCAVVGRQDH 522

  Fly   471 VSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLSGAYHIRGGVYFIDSLPKTPNDKLQRRKV 533
            |:..:.|..||  |:.:...|.:..:|..|...::....:||||:||..:|::...|:.||.:
 Worm   523 VTGEVPAAFVV--KNAQHPLLASAEVRQYVSGKIATFKELRGGVFFISEIPRSVCGKILRRNL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	Firefly_Luc_like	45..529	CDD:341237	107/447 (24%)
mec-18	NP_508731.3	Firefly_Luc_like	35..579	CDD:341237	107/447 (24%)