DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	528	Identity:	121/528 - (22%)
Similarity:	205/528 - (38%)	Gaps:	133/528 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RIAQAFKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVI 130
            ::|:.|.:|||.|...|.|...||.......:..:..|..:..::...:.|..:|:.......||
  Rat   141 KVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRANVI 205

  Fly   131 FCDVENY------------HIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLN-----DEDSITA 178
            ..|.:..            | :|.|....:.|.|      |:..|..:.|::.     .|:::.|
  Rat   206 VVDTQKQLEKILKIWKDLPH-LKAVVIYQEPPPK------KMANVYTMEELIELGQEVPEEALDA 263

  Fly   179 AAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSLLCNCKNPNTYT---------------RD 228
            ......|    :....:|.:|||||.||||..|..::        |:|               :.
  Rat   264 IIDTQQP----NQCCVLVYTSGTTGNPKGVMLSQDNI--------TWTARYGSQAGDIQPAEVQQ 316

  Fly   229 SVLLSFSPLYWISGTI-------------------ILLASLLNGCRRIITNRPYS---------- 264
            .|::|:.||..|:..|                   .|..:|:|..|.:   .|.|
  Rat   317 EVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFADPDALKGTLVNTLREV---EPTSHMGVPRVWEK 378

  Fly   265 -VEYLLQLVA-----RHKVTFLFLASHQIAL---LSKHDSDVMELKAQLQSIRVLIGAGSKVCKA 320
             :|.:.::.|     |.|   :.|.:..:.|   |:...:|:....::|....||......:..|
  Rat   379 IMERIQEVAAQSGFIRRK---MLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFA 440

  Fly   321 VCRRMYE------------LIG-NQRFVVGYGLSEMGG---LSKNVGGPVGCEGKVMRNVELRVL 369
            .|::.:.            .:| |.|...||||||..|   :|......:...|:|:....::::
  Rat   441 KCQKNFYGAAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLV 505

  Fly   370 DKLKMPLGINEVGIIYARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDT 434
            :  :...||.|: .::.|..|  .||....:.|..|:.|:| |..|||:|.||.:|:|||..|..
  Rat   506 N--QDADGIGEI-CLWGRTIF--MGYLNMEDKTHEAIDSEG-WLHTGDMGRLDDDGFLYITGRLK 564

  Fly   435 D-VFKFNNFQIYPEQIEEFI-LRLPGVSEACVFGIPDA---VSTNLT-ACAVVRTKSPEGERLTA 493
            : :.......:.|..|||.: :.||.:|.|.:.|  |.   :|..|| .|    |.:||    |:
  Rat   565 ELIITAGGENVPPVPIEEAVKMELPIISSAMLIG--DQRKFLSMLLTLKC----TLNPE----TS 619

  Fly   494 DHIRNIVE 501
            :...|:.|
  Rat   620 EPTDNLTE 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	121/528 (23%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	121/528 (23%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	121/528 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342869
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930