DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17999 and acsm3

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_002932029.3	Gene:	acsm3 / 100491087	XenbaseID:	XB-GENE-486978	Length:	581	Species:	Xenopus tropicalis

Alignment Length:	531	Identity:	121/531 - (22%)
Similarity:	215/531 - (40%)	Gaps:	85/531 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DTTGQELTGA--QLAQQSARIAQAFK-RLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLH 110
            |.:|:|:..:  :|...|.:.|.... ...|:.||.|.:..........:.:|.:..|:.:.|..
Frog    82 DGSGEEVKWSFEELGFLSRKAANVLSDACNLKPGDRVIVILPRVPEWWLLNVACIRAGVVLIPGT 146

  Fly   111 PEFTEETVKYMYDITEPKVIF---CDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLD---ISEM 169
            .:.|.:.:.:....:..|.|.   |.||....:...:..||  .|:.:...:.:|.||   :.::
Frog   147 TQLTAKDILHRLQTSMAKCIITSDCLVEAVDSVAAQSPFLQ--TKMLISTERRDGWLDFKGLFQV 209

  Fly   170 LNDEDSITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKGVTRSHRSLLCNCKNPNTYTRD------ 228
            .||:.:        |.|........|..:|||||.||....||.|.....|....|..|
Frog   210 ANDKHT--------CVKTKSSDPMTIFFTSGTTGSPKMTEHSHCSYGLGLKVNGKYWMDLTPTDI 266

  Fly   229 ---------------SVLLSFSPLYWISGTIILLASLLNGCRRIITNRPYSVEYLLQLVARHKVT 278
                           ||   |:|  ||.|:.:...|:    .|..||      .:|:.::...:|
Frog   267 VWNMSDTGWAKSAWSSV---FAP--WIQGSCVFAHSM----PRFDTN------IVLKTLSTFPIT 316

  Fly   279 FLFLA--SHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLS 341
            ....|  ::::.:|....|      .:.:|::..:.||..:...|..:..|..|...: .|||.:
Frog   317 TFCSAPTAYRMLVLQNFAS------YKFKSLQHCVSAGEPINPQVMEQWKEQTGLDIY-EGYGQT 374

  Fly   342 E---MGGLSKNVGGPVGCEGKVMRNVELRVLDKLKMPLGINEVGIIYARLRFK-----WAGYYRN 398
            |   :.|..|.:....|..||.....::.::|:....|...:.|.|..|:..:     ::.|..:
Frog   375 ETVLICGTFKGMKIKPGSMGKPSPAYDVEIVDENGNVLPQGKEGDIAIRILPQKPFCLFSQYTGD 439

  Fly   399 PEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYPEQIEEFILRLPGVSEAC 463
            ||  |.|.:..|.::.|||.|..|.:||.:...|..||...:.::|.|.::|..::..|.|:|:.
Frog   440 PE--RTASTRRGNFYLTGDRGIKDEDGYFWFVGRSDDVILSSGYRIGPFEVESALIEHPAVAESA 502

  Fly   464 VFGIPDAVSTNLTACAVVRTKSPEG---ERLT---ADHIRNIVEHHLSGAYHIRGGVYFIDSLPK 522
            |...||.:...:....||...:..|   |:|.   .:|:|||     :..|.....:.|:..|||
Frog   503 VVSSPDPIRGEVVKAFVVLAPAYNGYDPEKLALELQEHVRNI-----TAPYKYPRKIEFVQQLPK 562

  Fly   523 TPNDKLQRRKV 533
            |.:.|::|.::
Frog   563 TVSGKIRRNEL 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	121/531 (23%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	120/525 (23%)
acsm3	XP_002932029.3	MACS_euk	49..578	CDD:341251	121/531 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920