Protein Alignment sktl and MSS4

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_010494.1
• Gene: MSS4 / 851789
• SGDID: S000002616
• Length: 779
• Species: Saccharomyces cerevisiae
• Alignment Length: 625
• Identity: 170/625 - (27%)
• Similarity: 264/625 - (42%)
• Gaps: 141/625 - (22%)

  Fly    18 LKDQPDDENEPLENQLELEQEHKSLL-----TPVKIPPAQTASPDQEAT---------PSTPPPM 68
            :|.:.:.::..|.|......:|..:|     ..:|:....|:.....||         |..|.|.
Yeast   216 IKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQ 280

  Fly    69 SLQPGTSRQLFRDAAMAHGGQETTSLLQQE--------------------LNNIAATQTPASKL- 112
            ..|......:.        .:.||||..:.                    :||...|.|.|:.|
Yeast   281 PSQKSKQYHMI--------SKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLK 337

  Fly   113 RSASSTLDASISRNPSTTGGKHEKKLGHR-------RVAEGGEVTYKKIQ---SKQIMGSIQLGI 167
            ||.|:|  |.|.:...:...|.|.|...:       ||..|.:|:...:.   :..::..|::.:
Yeast   338 RSESAT--AEIKKMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTGIRVAV 400

  Fly   168 QHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAP 232
            ....|.:  ||   |...||...:.::|...|:.:||:..| .|:||.|.|..||..|.|||:.|
Yeast   401 SRCSGIM--KP---LTPADFRFTKKLAFDYHGNELTPSSQY-AFKFKDYCPEVFRELRALFGLDP 459

  Fly   233 DDFLMSMCAS-PLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPRTL 296
            .|:|:|:.:. .|.||::||.|||.||.:.|.::||||:...|...|:|.:..||.::..||.||
Yeast   460 ADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNPNTL 524

  Fly   297 LPKFFGLY------CFHYNSKN--VRLVAMNNLLPSDIKMHCKYDLKGSSFRR-----KASKAER 348
            :.:|:||:      .|....|:  :..:.||||.|..:.:|..||||||::.|     |...|:.
Yeast   525 ICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKD 589

  Fly   349 QKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEK 413
            :...|..|||::.|.... |.....|....::.:|:|..:|.....||||||:|||:::   |.|
Yeast   590 RSYRPVMKDLNWLEEGQK-IKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDIN---KAK 650

  Fly   414 REERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNR 478
            .::..|...|.:: ::...|||..                          |..|.
Yeast   651 EDDLQLADTASIE-EQPQTQGPIR--------------------------TGTGT---------- 678

  Fly   479 QRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSE--NDERLILYIGIIDILQSYRLEKKLEH 541
              :|.|.             ..|.|    |||.|..:  ||..||.|:||||.|.:|.:.||||.
Yeast   679 --VVRHF-------------FREFE----GGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLET 724

  Fly   542 TFKSILYNGDTVSVCRPSFYAKRF----QDAMGKQVFKKT 577
            .::|:.::...||...|..||.||    :|::.....|||
Yeast   725 FWRSLRHDTKLVSAIPPRDYANRFYEFIEDSVDPLPQKKT 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	126/409 (31%)
MSS4	NP_010494.1	MSS4	4..772	CDD:227578	170/625 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I904
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I899
Isobase	1	0.950	-	0	Normalized mean entropy	S1569
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46604
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.770