DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sktl and PIP5K2

DIOPT Version :9

Sequence 1:	NP_001286646.1	Gene:	sktl / 37356	FlyBaseID:	FBgn0016984	Length:	792	Species:	Drosophila melanogaster
Sequence 2:	NP_001319397.1	Gene:	PIP5K2 / 844110	AraportID:	AT1G77740	Length:	754	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	160/462 - (34%)
Similarity:	239/462 - (51%)	Gaps:	62/462 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 RNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWE 189
            :||....|:.:|.         ||...|..:...:|.::|.||:::||..|| ..|||..:||..
plant   334 KNPCCFSGEAKKP---------GETISKGHKKYDLMLNLQHGIRYSVGKHAS-VVRDLKQSDFDP 388

  Fly   190 METI--SFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCAS-PLRELSNPG 251
            .|..  .|||:||..||.|...|||:|.|.|:.||..|:||.:.|.|:::::|.: .|||||:||
plant   389 SEKFWTRFPPEGSKTTPPHLSVDFRWKDYCPLVFRRLRELFTVDPADYMLAICGNDALRELSSPG 453

  Fly   252 ASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPRTLLPKFFGLYCFH-YNSKNVRL 315
            .|||.||||.||.|:||||:|.|.:.|.::||.||.::.|...||:.:|:|::|.. ...:..|.
plant   454 KSGSFFYLTQDDRFMIKTVKKSEVKVLLRMLPSYYKHVCQYENTLVTRFYGVHCIKPVGGQKTRF 518

  Fly   316 VAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQ-KASPTFKDLDFAEHHPNGIF-LETDKYNAL 378
            :.|.||..|:.::..::||||||..|..||.|.: ..:.|.||||.     |..| |:.:.|..|
plant   519 IVMGNLFCSEYRIQRRFDLKGSSHGRYTSKPEGEIDETTTLKDLDL-----NFAFRLQRNWYQEL 578

  Fly   379 MSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDD 443
            |:.|||||..||:.:|||||||||:|..|....:|.                      .|:|
plant   579 MTQIKRDCEFLEAERIMDYSLLVGVHFRDDNTGDKM----------------------GLSP--- 618

  Fly   444 APEADQNQLQA--VASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLE------ 500
                  ..|::  :.||.| .....|.........:..|::|....|..:.|:|....|
plant   619 ------FVLRSGKIESYQS-EKFMRGCRFLEAELQDMDRILAGRKPLIRLGANMPARAERMARRS 676

  Fly   501 EDEDVPAGGIPARSEND-ERLILYIGIIDILQSYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKR 564
            :.:...:||...:|..: ..::||.|||||||.|.:.||:||.:||:..:..::|...|..|::|
plant   677 DYDQYSSGGTNYQSHGEVYEVVLYFGIIDILQDYDISKKIEHAYKSLQADPASISAVDPKLYSRR 741

  Fly   565 FQDAMGK 571
            |:|.:.:
plant   742 FRDFISR 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	142/404 (35%)
PIP5K2	NP_001319397.1	PLN03185	73..750	CDD:215619	160/462 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.820