Protein Alignment sktl and PIP4K2B

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: XP_011523628.1
• Gene: PIP4K2B / 8396
• HGNCID: 8998
• Length: 443
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 133/501 - (26%)
• Similarity: 204/501 - (40%)
• Gaps: 104/501 - (20%)

  Fly   109 ASKLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQ----SKQIMGSIQLGIQH 169
            :|...|.::...|.:|.:.:.|..||              ...:|::    |:.|:..:..|:.|
Human     2 SSNCTSTTAVAVAPLSASKTKTKKKH--------------FVCQKVKLFRASEPILSVLMWGVNH 52

  Fly   170 TVGSLASKPKRDLLM-NDFWEMETISFPPDGSSITPAHHYND------FRFKVYAPIAFRYFRDL 227
            |:..|::.|...:|| :||.....|.        ...|.:|.      |:||.|.|:.||..|:.
Human    53 TINELSNVPVPVMLMPDDFKAYSKIK--------VDNHLFNKENLPSRFKFKEYCPMVFRNLRER 109

  Fly   228 FGIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQ- 291
            |||...|:..|:..|......:.|..|:.|..|.|..|:||||..::...:..:|..|:.....
Human   110 FGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQMAGSL 174

  Fly   292 ---------------------------NPRTLLPKFFGLYCFHYNSKNVRLVAMNNLLPSDIKMH 329
                                       :..||||:|.|:|....:.....:|...|:....:.:|
Human   175 ACLCILSLPCGIPISGWQKRCKFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVH 239

  Fly   330 CKYDLKGSSFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQI 394
            .|||||||:..|:||..|:.|..|||||.||..........|..|.| .:..:|||...|...:|
Human   240 RKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKN-FLEKLKRDVEFLAQLKI 303

  Fly   395 MDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYA 459
            ||||||||||::|.|.:|:.|   :..||                 :|:..|.|......:.||.
Human   304 MDYSLLVGIHDVDRAEQEEME---VEERA-----------------EDEECENDGVGGNLLCSYG 348

  Fly   460 SIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYI 524
            : |..|.|..|:..|...                    |.|.|..|....:.:...:.::.:.::
Human   349 T-PPDSPGNLLSFPRFFG--------------------PGEFDPSVDVYAMKSHESSPKKEVYFM 392

  Fly   525 GIIDILQSYRLEKKLEHTFKSILYN-GDTVSVCRPSFYAKRFQDAM 569
            .|||||..|..:||..|..|::.:. |..:|...|..|:|||.:.|
Human   393 AIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFM 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	118/423 (28%)
PIP4K2B	XP_011523628.1	PIPKc	39..443	CDD:238081	125/450 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820