Protein Alignment sktl and Pip5kl1

DIOPT Version :10

• Sequence 1: NP_477206.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_001418700.1
• Gene: Pip5kl1 / 687758
• RGDID: 1597527
• Length: 606
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 145/669 - (21%)
• Similarity: 226/669 - (33%)
• Gaps: 206/669 - (30%)

  Fly    11 PVGKQDRLKDQPDDENEPLENQLELEQEHKSLLTPVKIPPAQTASPDQEATPSTPPPMSLQPGTS 75
            |.|.:.|.|       ..|..:..|:..::|   |. |||:|..|.:..|:....|     .|..
  Rat    19 PRGVRPRFK-------RKLRGESSLQHPNQS---PT-IPPSQNQSSEDAASSGVEP-----KGKG 67

  Fly    76 RQLFRDAA-----------MAHGGQETTSLLQQ--------ELNNIAATQTPASKLRSASSTL-- 119
            ::.||..:           :.|..|||.|...|        |:......:.|..:|..||:|:
  Rat    68 QRRFRGLSAKRTTVTRRPFLRHLSQETQSGQDQGSEDPASPEVGPAGKGKRPPGELSPASATVAG 132

  Fly   120 -----------------------DASISRNPSTTGGKHEKKLGHR---------RVAEG------ 146
                                   .||:...|:..|.:..::||.:         |.||.
  Rat   133 RPFPRYLSRRQAALKDQDQSSEDAASLEVGPAGKGKRPSRRLGRKVTGTPRLAVRNAEAEPDSCN 197

  Fly   147 ------------GEVTYKKIQSKQIMG-SIQLGIQHT------------------VGSLASKPKR 180
                        |.:....:.|::|.. |:.:|.:.|                  ||.....|..
  Rat   198 PASEPNQEKLHLGAMAALSLGSREIPSHSLDVGNRSTSSGSRRGLFWHLRAKHSRVGLFEIGPGH 262

  Fly   181 DL------LMNDFWEMETISF--PPDGS-------SITPAHHYNDFRFKVYAPIAFRYFRDLFGI 230
            :|      :....|....:|.  ||.|.       .:....|...|.....|..||...|...|:
  Rat   263 ELHRMTRMMQEGLWAATQVSMNNPPTGPPTQKDFLEVMTQVHKEGFELGTLAGPAFARLRQSIGL 327

  Fly   231 APDDFLMSM-CASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPR 294
            ..:|:..:: ...|..:..:...|.:.|:|:.|..|.:||.:::|.:.|...||.|..:|.|.|.
  Rat   328 TEEDYQATLGPGDPYLQFLSTSKSKASFFLSHDQRFFVKTQRRQEVQVLLAHLPRYVRHLQQYPH 392

  Fly   295 TLLPKFFGLYCFHY-NSKNVRLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKASP---TF 355
            :||.:..|:|.... ..|....:.|..:.....::..:||:||....|.....  .:.||   ..
  Rat   393 SLLARLLGVYSLRVAQGKKKYFIIMQCIFYPTSRISERYDIKGCEVSRWVDPV--PEGSPLLLVL 455

  Fly   356 KDLDFAEHHPNGIFLETDKYNALMSTIKR----DCMVLESFQIMDYSLLVGIHNLDLAAKEKREE 416
            |||:|.|        :|.|.....|...|    |...|....::|||||||:..|.  ..||.:.
  Rat   456 KDLNFRE--------KTIKLGTQRSWFLRQMALDTAFLRELNVLDYSLLVGVQFLH--KDEKVDY 510

  Fly   417 RILNARAKLQRKESAAQG-PPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQR 480
            ..|....|      :.|| |.|.|.|                                 ..||:.
  Rat   511 HCLIGTIK------SVQGAPKSENKD---------------------------------GQNRRM 536

  Fly   481 LVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKS 545
            |.....||..:            |.|          |:|  .::|::|:...|...|:|||.:|.
  Rat   537 LPNLPNALHIV------------DGP----------DQR--YFLGLVDLTTVYGFRKRLEHLWKM 577

  Fly   546 ILYNGDTVSVCRPSFYAKR 564
            :.|.|.:||...|:.||:|
  Rat   578 VRYPGQSVSTVSPAHYARR 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_477206.1	PIPKc_PIP5KI	158..577	CDD:340438	104/451 (23%)
Pip5kl1	NP_001418700.1	PHA03307	16..>203	CDD:223039	39/199 (20%)
		PIPKc_PIP5KL1	262..604	CDD:340441	97/410 (24%)