Protein Alignment sktl and PIP5K59B

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 377/748 - (50%)
• Similarity: 471/748 - (62%)
• Gaps: 142/748 - (18%)

  Fly    84 MAHGGQETTSLLQQELNNIAATQTPASKLRSAS------STLDASISRNPSTTGGKHEKKLGHRR 142
            ||.|..:|.:.:  ::::.:|:|...::..:||      |:.|.....|.:::....|:|:||||
  Fly     1 MASGDGDTINTI--DMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRASSKADKERKIGHRR 63

  Fly   143 VAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHH 207
            |.||||:||||||:.|||||||||||||||||||||||||||.||||:|:|:|||:|||:|||||
  Fly    64 VGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHH 128

  Fly   208 YNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQK 272
            |::||:|:|||||||||||||||.||||:||||.||||||||||||||||||||||||||||||.
  Fly   129 YSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQH 193

  Fly   273 KECEFLQKLLPGYYMNLSQNPRTLLPKFFGLYCFH-YNSKNVRLVAMNNLLPSDIKMHCKYDLKG 336
            ||.||||||||||||||:|||||||||||||||.. .|:||:|||.|||||||.:|||.||||||
  Fly   194 KEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKG 258

  Fly   337 SSFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLV 401
            |:|:|||:||||.|.|||:|||||.|.||||||||.:.|.||:.||:|||.|||||:|||||||:
  Fly   259 STFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLL 323

  Fly   402 GIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSA 466
            |:||||:|.|||:.|         |||...|  |.:.:.|.||.:             .:.| .|
  Fly   324 GVHNLDVALKEKQSE---------QRKPLRA--PLAEDSDVDADD-------------PLDG-DA 363

  Fly   467 GAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQ 531
            ...::|.:|:|||||||||||:|||.|:.: |::::||||.||||||||..|||:||||||||||
  Fly   364 ATGISRNKSVNRQRLVAHSTAMESIQAESE-PIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQ 427

  Fly   532 SYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKRFQDAMGKQVFKKTPT----------------- 579
            ||||:||||||||||:::|:|||||||||||:|||:.|.|.||:|.|:
  Fly   428 SYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLV 492

  Fly   580 ---FPLKHSPSKRKTSTTQL-RSPASRLPPLSTPTNA--------VRQPIMTMSGMSTPPPAFDD 632
               ..|||||||||:.:..: ||..|.....|.|.:|        :.||       :.||
  Fly   493 TSYIALKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHSHSSGKIHQP-------AKPP----- 545

  Fly   633 ISEEDITAASTSSLQQQRSSNQSNNNRGETEVALREGNNTRGGSGEPSSTYHTQYSYDSSGRTGS 697
             :.|...|.:....:           ||.|.:    |..|..|:.|.:.....|       ||.:
  Fly   546 -TTEPTPAGAAGGAE-----------RGATAL----GPATTSGASERAPPPVKQ-------RTPA 587

  Fly   698 ALTSDYSDDESTGTDLSSRLPKLRTHRLTKTSVQVTTVGYVEGVDTPPKGGQDVVHADVNGKTTM 762
            |            ::|.:|:|.                      ..||:|...  ..|...:||.
  Fly   588 A------------SNLKTRVPP----------------------PVPPRGSPR--RKDAQDRTTP 616

  Fly   763 TTTTMLTTTKTAHIQAPSYTSTLVL---NDLPR 792
            .|....|...    .||::|.||.:   ..:||
  Fly   617 GTEPHTTNPN----PAPAHTHTLQVPANEGIPR 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	270/390 (69%)
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	297/420 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449914
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
Isobase	1	0.950	-	0	Normalized mean entropy	S1569
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm6440
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	P	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X284
	12	11.750