Protein Alignment sktl and Pip5k1c

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: XP_008763323.1
• Gene: Pip5k1c / 314641
• RGDID: 1309938
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 718
• Identity: 298/718 - (41%)
• Similarity: 397/718 - (55%)
• Gaps: 155/718 - (21%)

  Fly    81 DAAMAHGGQETTSLLQQELNNIAATQTPASKLRSASSTLDASISRNPSTTGGK---HEKKLGHRR 142
            :|..|..|..|........:..||..|...          |.::..|..||..   |.||||||.
  Rat     8 EAESAEAGAVTAEAAWSAESGAAAGMTQKK----------AILAEAPLVTGQPGPGHGKKLGHRG 62

  Fly   143 VAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHH 207
            |...||.||||..|..:.|:|||||.:|||:|:|||:||:||.||:.:|:|.||.:||::|||||
  Rat    63 VDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHH 127

  Fly   208 YNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQK 272
            :.|||||.|||:||||||:||||.|||:|.|:|..||.||||||||||:||:|:|||||||||..
  Rat   128 FQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMH 192

  Fly   273 KECEFLQKLLPGYYMNLSQNPRTLLPKFFGLYCFHYNSKNVRLVAMNNLLPSDIKMHCKYDLKGS 337
            ||.||||||||||||||:||||||||||:||||.....||:|:|.|||:||..:|||.|:|||||
  Rat   193 KEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGS 257

  Fly   338 SFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVG 402
            :::|:|||.|::|:.||:|||||.:..|.|:.|::|.:.||:.|::|||:|||||:|||||||:|
  Rat   258 TYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLG 322

  Fly   403 IHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAG 467
            :||:|   :::||.:...|::|...|...||
  Rat   323 VHNID---QQERERQAEGAQSKADEKRPVAQ---------------------------------- 350

  Fly   468 AALNRTRSMNRQRLVAHSTALESIT--ADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDIL 530
            .||             :|||:|||.  |.....:|.|:.:  |||||.:...|||:|:|||||||
  Rat   351 KAL-------------YSTAMESIQGGAARGEAIETDDTM--GGIPAVNGRGERLLLHIGIIDIL 400

  Fly   531 QSYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKRFQDAMGKQVFKKTPTFPLKHSPSKRKTSTTQ 595
            ||||..||||||:|:::::||||||.||||||:||...|...||:|:.:  ||.||||:......
  Rat   401 QSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSS--LKSSPSKKGRGALL 463

  Fly   596 LRSP--------ASRLPPLSTPTNAVRQPIM----------TMSGMSTP------PPAFDDISEE 636
            ...|        ||::|       :.|:.:.          |:.....|      ||:|::.:..
  Rat   464 AVKPLGPTAAFSASQIP-------SEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTA 521

  Fly   637 DI--TAASTS-SLQQQRSSNQSNNNRGETEVALREGNNTRGGSGEPSSTYHTQYSYDSSGRTGSA 698
            .|  |.:||| |:.::..|:.|...|      .|....:.|..|.|....|.:
  Rat   522 SIATTLSSTSLSIPERSPSDTSEQPR------YRRRTQSSGQDGRPQEELHAE------------ 568

  Fly   699 LTSDYSDDESTGTDLSSRLPKLRTHRLTKTSVQVTT---VGYV------EGVDTPPKGGQDVVHA 754
                                     .|.|.:|||..   ||.|      .||:.||.|.......
  Rat   569 -------------------------DLQKITVQVEPVCGVGVVVPKEQGAGVEVPPSGASAAATV 608

  Fly   755 DVN 757
            :|:
  Rat   609 EVD 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	210/391 (54%)
Pip5k1c	XP_008763323.1	PIPKc	103..443	CDD:214623	210/391 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	363	1.000	Domainoid score	I912
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	496	1.000	Inparanoid score	I1334
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm8996
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830