Protein Alignment sktl and Pip5k1a

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: XP_036018829.1
• Gene: Pip5k1a / 18720
• MGIID: 107929
• Length: 560
• Species: Mus musculus
• Alignment Length: 564
• Identity: 270/564 - (47%)
• Similarity: 353/564 - (62%)
• Gaps: 83/564 - (14%)

  Fly   111 KLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLA 175
            |..:||....|::|..||.: ....||:|||.|...||.||||..|..:.|:|||||.||||||:
Mouse    37 KRAAASGIKRATVSEGPSAS-VMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLS 100

  Fly   176 SKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDDFLMSMC 240
            :||:||:||.||:.:|:|.||.:||::||||||||||||.|||:||||||:||||.|||:|.|:|
Mouse   101 TKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLC 165

  Fly   241 ASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPRTLLPKFFGLYC 305
            :.||.||||.|||||:||:::||||||||||.||.||||||||||||||:||||||||||:||||
Mouse   166 SEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYC 230

  Fly   306 FHYNSKNVRLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKASPTFKDLDFAEHHPNGIFL 370
            .....||:|:|.||||||..:|||.|||||||:::|:||:.||:|..||||||||.:..|:|:||
Mouse   231 VQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFL 295

  Fly   371 ETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGP 435
            :.|.|:||..|::|||:||:||:|||||||:.|||:|.|.:|
Mouse   296 DADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQRE----------------------- 337

  Fly   436 PSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLE 500
                     |.::..|..|                 .||....|:.: :|||:|||..:......
Mouse   338 ---------PTSNDTQYSA-----------------DTRRPAPQKAL-YSTAMESIQGEARRGGT 375

  Fly   501 EDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKSILYNGDTVSVCRPSFYAKRF 565
            .:.:...||||||:...|||:|||||||||||||..|||||::|:::::||||||.||.|||:||
Mouse   376 VETEDHMGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERF 440

  Fly   566 QDAMGKQVFKKTPTFPLKHSPSKR---------------KTSTTQLRSPASRLPPLSTPTNA--- 612
            |..|...||||   .|||.||:|:               .:.|:||.:.......::|....
Mouse   441 QRFMCNTVFKK---IPLKPSPTKKFRSGPSFSRRSGPSGNSCTSQLMASGEHRAQVTTKAEVEPD 502

  Fly   613 ----------VRQPIMTMS-GMSTPPPAFDDISEEDITAASTSS 645
                      ...|:..:| |...|.|:|..:..:.:...:.||
Mouse   503 VHLGRPDVLPQTPPLEEISEGSPVPGPSFSPVVGQPLQILNLSS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	212/389 (54%)
Pip5k1a	XP_036018829.1	PIPKc_PIP5K1A_like	79..454	CDD:340443	233/427 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837828
Domainoid	1	1.000	364	1.000	Domainoid score	I934
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1246
Isobase	1	0.950	-	0	Normalized mean entropy	S1569
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm8752
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.710