Protein Alignment sktl and Pip4k2a

DIOPT Version :9

• Sequence 1: NP_001286646.1
• Gene: sktl / 37356
• FlyBaseID: FBgn0016984
• Length: 792
• Species: Drosophila melanogaster
• Sequence 2: NP_032871.3
• Gene: Pip4k2a / 18718
• MGIID: 1298206
• Length: 405
• Species: Mus musculus
• Alignment Length: 474
• Identity: 115/474 - (24%)
• Similarity: 200/474 - (42%)
• Gaps: 100/474 - (21%)

  Fly   119 LDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQ----SKQIMGSIQLGIQHTVGSLA---- 175
            |.:|:..:.:.|..||              ...:|::    |..::..:..|:.|::..|:
Mouse     7 LGSSVLASKTKTKKKH--------------FVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQI 57

  Fly   176 ------------SKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLF 228
                        ||.|.|   |..:..|.:          |:|    |:||.|.|:.||..|:.|
Mouse    58 PVMLMPDDFKAYSKIKVD---NHLFNKENM----------PSH----FKFKEYCPMVFRNLRERF 105

  Fly   229 GIAPDDFLMSMCASPLRELSNPGASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQ-N 292
            ||...||..|:..|......:...||:.|:.:.|..::|||:..::...:..:|..|:..:.: :
Mouse   106 GIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYVIKTITSEDVAEMHNILKKYHQYIVECH 170

  Fly   293 PRTLLPKFFGLYCFHYNSKNVRLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKASPTFKD 357
            ..||||:|.|:|..:.:...:.::...|:....:.::.|||||||:..|:||..|:.|..||.||
Mouse   171 GVTLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKD 235

  Fly   358 LDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNAR 422
            .||. :....|:::.:.....:..:|:|...|...::||||||||||:::.|.:|:.|
Mouse   236 NDFI-NEGQKIYIDDNNKKIFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVE------- 292

  Fly   423 AKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTA 487
                           ...:|...|.:.:....:.:    |..|.|..||.:..:
Mouse   293 ---------------CEENDGEEEGESDSTHPIGT----PPDSPGNTLNSSPPL----------- 327

  Fly   488 LESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHTFKSILYN-GD 551
                     .|.|.|.::....|........:.:.::.|||||..|..:||..|..|::.:. |.
Mouse   328 ---------APGEFDPNIDVYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGA 383

  Fly   552 TVSVCRPSFYAKRFQDAMG 570
            .:|...|..|:|||.|.:|
Mouse   384 EISTVNPEQYSKRFLDFIG 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sktl	NP_001286646.1	PIPKc	183..573	CDD:214623	101/390 (26%)
Pip4k2a	NP_032871.3	Required for interaction with PIP5K1A. /evidence=ECO:0000250|UniProtKB:Q8TBX8	59..65		0/5 (0%)
		PIPKc	62..405	CDD:214623	105/405 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	288..328		9/85 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810