DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13442 and MARCHF7

DIOPT Version :9

Sequence 1:	NP_611511.3	Gene:	CG13442 / 37349	FlyBaseID:	FBgn0034546	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001269734.1	Gene:	MARCHF7 / 64844	HGNCID:	17393	Length:	704	Species:	Homo sapiens

Alignment Length:	209	Identity:	47/209 - (22%)
Similarity:	68/209 - (32%)	Gaps:	79/209 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LSDLKPETTLEMEIDEALSSSSADDTPPGMIVVETRISSWQKVKCYDKDGTTADAEDPQIPACSL 87
            :|.:.|.:.....:..||.|:..|:.   ||.|:...|.|...........:|.:.||:
Human   475 ISGILPGSLFRFAVPPALGSNLTDNV---MITVDIIPSGWNSADGKSDKTKSAPSRDPE------ 530

  Fly    88 GLKPNVQFQKLPHPSHPLVSTEAVLAAATSSSYSAGPPKAAATDSIATLRHCVDGATQCNNLNYE 152
                  :.||:.                                               .:|..|
Human   531 ------RLQKIK-----------------------------------------------ESLLLE 542

  Fly   153 SASNESMPSVGSLVCRICH--NADNPEQLVSPCLCKGSLTYVHVHCLECWI--------STSRCT 207
            .:..|.    |.| ||||.  .|.:...|:.||.|.|||.|||..|::.|:        |....|
Human   543 DSEEEE----GDL-CRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVT 602

  Fly   208 TCELC--QFQYNTE 219
            |||||  :.:.|.|
Human   603 TCELCKEKLELNLE 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	AmyAc_family	<36..>151	CDD:298606	15/114 (13%)
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	24/58 (41%)
MARCHF7	NP_001269734.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..126
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..279
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..313
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..343
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	361..425
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	444..473
		RING_Ubox	552..610	CDD:388418	24/57 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	683..704
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810