DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13442 and MARCHF2

DIOPT Version :9

Sequence 1:NP_611511.3 Gene:CG13442 / 37349 FlyBaseID:FBgn0034546 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001005415.1 Gene:MARCHF2 / 51257 HGNCID:28038 Length:246 Species:Homo sapiens


Alignment Length:215 Identity:62/215 - (28%)
Similarity:91/215 - (42%) Gaps:45/215 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 GPPKAAATDS------IATLRHCVDGATQCNNLNYESASNESMPSVGSLVCRICHNADNPEQLVS 181
            |||:..|..:      ::|:...:|                 .||.|.. |||||...|.|.|:|
Human    32 GPPQYVAQVTSRDGRLLSTVIRALD-----------------TPSDGPF-CRICHEGANGECLLS 78

  Fly   182 PCLCKGSLTYVHVHCLECWISTSRCTTCELCQFQYNTEQTLRYTCLQSLRLWY---SRAMSRRAL 243
            ||.|.|:|..||..|||.|:|:|..:.||||..::..|:..|     .|..|.   .....:|.|
Human    79 PCGCTGTLGAVHKSCLEKWLSSSNTSYCELCHTEFAVEKRPR-----PLTEWLKDPGPRTEKRTL 138

  Fly   244 QEDCQMFSLLTLVAFGIIGTL-LVGIQ-YYALHT--HSWGLSKLWTKSWMLFFLFMTITV-YFAN 303
            ..|...|..:|.:| .|.|.| |.|.| :..||:  .:.||..|....:.::.|:..::. |...
Human   139 CCDMVCFLFITPLA-AISGWLCLRGAQDHLRLHSQLEAVGLIALTIALFTIYVLWTLVSFRYHCQ 202

  Fly   304 IYMLIKSQLTPWYRWWQSAR 323
            :|       :.|.:..|..|
Human   203 LY-------SEWRKTNQKVR 215

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13442NP_611511.3 AmyAc_family <36..>151 CDD:298606 6/33 (18%)
RINGv 166..213 CDD:128983 25/46 (54%)
MARCHF2NP_001005415.1 RING_CH-C4HC3_MARCH2 62..113 CDD:319722 26/51 (51%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 61 1.000 Domainoid score I10485
eggNOG 1 0.900 - - E1_COG5183
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000792
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR46065
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4119
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.940

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