DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13442 and Marchf11

DIOPT Version :9

Sequence 1:	NP_611511.3	Gene:	CG13442 / 37349	FlyBaseID:	FBgn0034546	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001095298.1	Gene:	Marchf11 / 499558	RGDID:	1559945	Length:	398	Species:	Rattus norvegicus

Alignment Length:	272	Identity:	63/272 - (23%)
Similarity:	104/272 - (38%)	Gaps:	70/272 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 EAVLAAATSSSYSAGPPKAAA--------------TDSIATLRHCVDGATQCNNLNYESASNESM 159
            |..|..|.:...|...|:|.|              |.|:.:.|....|.:......::...::.
  Rat   101 EVKLPEAAAGKGSPAEPEAGACGEGERRGTGDQPETRSVCSSRSSSSGGSGDQRSGHQHQHHQP- 164

  Fly   160 PSVGSLVCRICHNADNPEQLVSPCLCKGSLTYVHVHCLECWISTSRCTTCELCQFQYN-TEQTLR 223
                  :|:||.......:|::||.|.||:.|.|..||..|||.....|||||.::|: |...::
  Rat   165 ------ICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVTAIKMK 223

  Fly   224 YTCLQSLRLWYSRAMSRRALQEDCQMFSLLTLVAFGIIGTLLVGIQYYALHTHSWGLSKLWTKSW 288
            ..|     .|.|.:::   |.|..||.::       |:|:|.:......|...::....:|.:..
  Rat   224 QPC-----QWQSISIT---LVEKVQMIAV-------ILGSLFLIASVTWLLWSAFSPYAVWQRKD 273

  Fly   289 MLF------FLFMTITVY------FANIYMLIKSQLTPWYRW-----------WQSARDIKLILE 330
            :||      :.||.:...      .|.:|.:.|       ||           :..|.||:   |
  Rat   274 ILFQICYGMYGFMDLVCIGLIVHEGAAVYRVFK-------RWRAVNLHWDVLNYDKATDIE---E 328

  Fly   331 NRRPFPNPSRFL 342
            :.|...:.||.|
  Rat   329 SSRGESSTSRTL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	AmyAc_family	<36..>151	CDD:298606	11/55 (20%)
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	20/46 (43%)
Marchf11	NP_001095298.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..158		11/56 (20%)
		RING_CH-C4HC3_MARCH4_like	165..215	CDD:319614	21/49 (43%)
		YXXL motif	367..370
		PDZ-binding	395..398
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810