DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13442 and Marchf4

DIOPT Version :9

Sequence 1:	NP_611511.3	Gene:	CG13442 / 37349	FlyBaseID:	FBgn0034546	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001038998.1	Gene:	Marchf4 / 381270	MGIID:	2683550	Length:	409	Species:	Mus musculus

Alignment Length:	300	Identity:	71/300 - (23%)
Similarity:	113/300 - (37%)	Gaps:	79/300 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 SAGPPKAAATDSIATLRHCVDGATQCNNLNYESASNESMPSVGSLVCRICHNADNPEQLVSPCLC 185
            :.||| |:...|.::...|.:....|.:|.....|....|     :||||.......:|:|||.|
Mouse   122 ATGPP-ASLLSSASSDEFCKEKTEDCYSLGSSLDSGMRTP-----LCRICFQGPEQGELLSPCRC 180

  Fly   186 KGSLTYVHVHCLECWISTSRCTTCELCQFQYNTEQTLRYTCLQSLRLWYSRAMSRRALQEDCQMF 250
            .||:...|..||..|||...|.:||||.::|:.........||    |  :|:|...:::
Mouse   181 DGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQ----W--QAISLTVIEK----- 234

  Fly   251 SLLTLVAFGIIGTLLVGIQYYALHTHSWGL------SKLWTKSWMLF------FLFMTITVY--- 300
               ..:|..|:|:|      :.:.:.||.:      |..|.:..:||      :.||.:...
Mouse   235 ---VQIAAAILGSL------FLIASISWLIWSTFSPSAKWQRQDLLFQICYGMYGFMDVVCIGLI 290

  Fly   301 ---FANIYMLIKSQLTPWYRWWQSARDIKLILENRRPFPNPSRFLRSFQLETVSTTASMYTHHDQ 362
               ..::|.:.|.        ||:......:|          .:.::..||            ||
Mouse   291 IHEGPSVYRIFKR--------WQAVNQQWKVL----------NYDKTKDLE------------DQ 325

  Fly   363 QEAP----VPSSSPVIVITSSEEETEDKLAHKWG-TRLDS 397
            :...    ..|||....:.|:|||.....|.:.| ||..|
Mouse   326 KSGGRTNLQTSSSAQANLPSAEEEAASPPAREEGPTRAAS 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	AmyAc_family	<36..>151	CDD:298606	8/29 (28%)
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	21/46 (46%)
Marchf4	NP_001038998.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..133		4/11 (36%)
		RING_CH-C4HC3_MARCH4_9	161..211	CDD:319725	22/49 (45%)
		RING-CH finger (C4HC3-type)	162..207	CDD:319725	20/44 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	323..372		14/54 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..409
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810