DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13442 and Marchf10

DIOPT Version :9

Sequence 1:	NP_611511.3	Gene:	CG13442 / 37349	FlyBaseID:	FBgn0034546	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001013995.1	Gene:	Marchf10 / 303596	RGDID:	1311692	Length:	790	Species:	Rattus norvegicus

Alignment Length:	350	Identity:	77/350 - (22%)
Similarity:	119/350 - (34%)	Gaps:	110/350 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RLNLTRSLSDLKPETTLEMEIDEALSSSSADDTPPGMIVVETRISSWQKVKCYDKDGTTADAEDP 80
            |.|:.|.||.::...      ..|.|.|.::||..    .|.|.|:.|.    .:....:|..:|
  Rat   500 RFNVRRPLSPIRNRN------PSAASESHSEDTQG----EEERASTSQA----QESPLLSDLPNP 550

  Fly    81 QIPACSLGLKPNVQFQKLPHPSHPLVSTEAVLAAATSS----SYSAGPPKAAATDSIATLRHCVD 141
            | .:.:||..|:       .|:...:.....:..:...    ::.|....|:..|:..::|  |.
  Rat   551 Q-SSMALGDSPS-------SPTRRHLQGHFYMPGSLQENIPFTFFAVSDFASQNDNGTSVR--VS 605

  Fly   142 G-----ATQCN------NLNYESASNESMPSVGSLVCRICHNAD----NPEQLVSPCLCKGSLTY 191
            |     ||:..      ....||...|.....|.| ||||..|.    ||  |:.||.|.|||.:
  Rat   606 GVMDEKATEIKADPEKLRKLQESLLEEDSEEEGDL-CRICQIAGGSPANP--LLEPCGCVGSLQF 667

  Fly   192 VHVHCLECWIST--------SRCTTCELCQFQYNTEQTLRYTCLQSLRLWYSRAMSRRALQEDCQ 248
            ||..||:.|:..        |...|||:|                           ::.|..|..
  Rat   668 VHQECLKKWLKVKITSGADLSTVKTCEMC---------------------------KQGLLVDLD 705

  Fly   249 MFSLLTLVAFGIIGTLLVGIQYYALHTHSWGLSKLWTKSWMLFFLFMTITVYFANIYMLIKSQLT 313
            .|::               .::|..|..|...|:|......|..|.......||.:       :|
  Rat   706 DFNM---------------TEFYHKHQQSRAQSELMNSGLYLVLLLHLYEQRFAEL-------MT 748

  Fly   314 PWYRWWQSARDIKLILENRRPFPNP 338
            ..||  :::|:     ...|.:|.|
  Rat   749 LNYR--RASRE-----RMSRNYPQP 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	AmyAc_family	<36..>151	CDD:298606	24/129 (19%)
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	23/58 (40%)
Marchf10	NP_001013995.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	33..240
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	323..416
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	507..569		18/83 (22%)
		RING_CH-C4HC3_MARCH10	641..700	CDD:319727	24/87 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	757..790		2/14 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900