DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13442 and MARCHF10

DIOPT Version :9

Sequence 1:	NP_611511.3	Gene:	CG13442 / 37349	FlyBaseID:	FBgn0034546	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_005257152.2	Gene:	MARCHF10 / 162333	HGNCID:	26655	Length:	863	Species:	Homo sapiens

Alignment Length:	246	Identity:	55/246 - (22%)
Similarity:	80/246 - (32%)	Gaps:	94/246 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 ESASNESMPSVGSLVCRICHNA----DNPEQLVSPCLCKGSLTYVHVHCLECWIST--------S 204
            ||...|.....|.| ||||..|    .||  |:.||.|.|||.:||..||:.|:..        .
Human   683 ESLLEEDSEEEGDL-CRICQIAGGSPSNP--LLEPCGCVGSLQFVHQECLKKWLKVKITSGADLG 744

  Fly   205 RCTTCELCQFQYNTEQTLRYTCLQSLRLWYSRAMSRRALQEDCQMFSLLTLVAFGIIGTLLVGIQ 269
            ...|||:|                           ::.|..|...|::               |:
Human   745 AVKTCEMC---------------------------KQGLLVDLGDFNM---------------IE 767

  Fly   270 YYALHTHSWGLSKLWTKSWMLFFLFMTITVYFANIYMLIKSQLTPWYRWWQSARDIKLILENRRP 334
            :|..|..|...::|......|..|.......||.:..|..:|                 :|..|
Human   768 FYQKHQQSQAQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQ-----------------VERER- 814

  Fly   335 FPNPSRFLRSFQLETVSTTASMYTHHDQQEA-------PVPSSSPVIVITS 378
                   :||:::|  ...|.:......:||       |:|   |.::.||
Human   815 -------IRSWEME--MKAAFLKARSSSKEANCGARRRPLP---PALLSTS 853

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	AmyAc_family	<36..>151	CDD:298606
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	22/58 (38%)
MARCHF10	XP_005257152.2	RINGv	697..753	CDD:128983	23/84 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900