Protein Alignment CG13442 and MARCHF6

DIOPT Version :10

• Sequence 1: NP_611511.3
• Gene: CG13442 / 37349
• FlyBaseID: FBgn0034546
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_005876.2
• Gene: MARCHF6 / 10299
• HGNCID: 30550
• Length: 910
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 70/291 - (24%)
• Similarity: 111/291 - (38%)
• Gaps: 89/291 - (30%)

  Fly   166 VCRICHNADNPEQ-LVSPCLCKGSLTYVHVHCLECWISTSRCTTCELCQFQYNTEQTLRYTCLQS 229
            :||:|.:...||: |..||:|.||:.::|..||..|:..||...||||:.::      .:|.:
Human     8 ICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRF------AFTPI-- 64

  Fly   230 LRLWYSRAM-SRRALQEDCQMFSLL--------------TLVAFGIIGTL-LVGIQYY-ALHTHS 277
                ||..| ||..:|:   :|:.|              |||||..:|.: |...:.| .|.|.|
Human    65 ----YSPDMPSRLPIQD---IFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGS 122

  Fly   278 WG------LSKLWTKSWM------LFFLFMTITVYFANIYMLIKSQLTPWYRWWQSARDIKLILE 330
            ..      |..|.|::.:      .|.:..|:..:.:.:          |.|        :.|:.
Human   123 VSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLV----------WLR--------EQIVH 169

  Fly   331 NRRPFPNPSRFLRSFQLETVSTTASMYTHHDQQEAPVPSSSPVIVITSSEEETEDKLAHKWGTRL 395
            ...|          ..||..:...:...|| |.|||...:       .:|....|:.|:.....
Human   170 GGAP----------IWLEHAAPPFNAAGHH-QNEAPAGGN-------GAENVAADQPANPPAEN- 215

  Fly   396 DSEVLAAVVAATVESIAD-ASARESDKQDED 425
                  |||....::..| |...|.|.::||
Human   216 ------AVVGENPDAQDDQAEEEEEDNEEED 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13442	NP_611511.3	RINGv	166..213	CDD:128983	20/47 (43%)
MARCHF6	NP_005876.2	RING_CH-C4HC3_MARCH6	8..57	CDD:438362	21/48 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	185..256		18/71 (25%)