DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fem-1 and AT4G03490

DIOPT Version :9

Sequence 1:	NP_611508.1	Gene:	Fem-1 / 37344	FlyBaseID:	FBgn0034542	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_001328102.1	Gene:	AT4G03490 / 827426	AraportID:	AT4G03490	Length:	710	Species:	Arabidopsis thaliana

Alignment Length:	707	Identity:	131/707 - (18%)
Similarity:	218/707 - (30%)	Gaps:	269/707 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DQPDGQSLTPLTMAAMMGNVKFVKTLLSHYDVDLDR------ECNVI-----YDGMVV----YGA 144
            ||...|..|.|.:||:.|:...|:.:|: |::::.|      .||.:     |..::|    .|.
plant    30 DQVTFQGNTILHLAAIYGHDHLVRRILA-YELNILRNWKRGLNCNFVPSFSHYQTLLVRRNYKGD 93

  Fly   145 TALWVAAGMGHLQIVKMLVQAGAAINHNTKAQSSPLRAACYEGRLDIVEFLIDNGADV--NATNL 207
            .||.|||..||..||.:|:.                   |.......:..:|.:...|  |...:
plant    94 LALHVAAAAGHKLIVGLLID-------------------CLRQLPQDITMVIGSEQMVIGNIFRV 139

  Fly   208 FNN--NTLMIAAYKGHHLVVK-------------------------------TLLQNGSRANDQA 239
            .||  ||.:..:.||:|:.|.                               :|:::..|..|.:
plant   140 SNNDGNTALHLSLKGNHVSVSLQLVREDRSTCFLLDKEDVSPLYMAAEAGYVSLVEHMLRGLDAS 204

  Fly   240 LCGATALHYAAESGHLDVVVALLDHGATL--KKNELGITPALQAAE------------RLHEDVL 290
            ..|.:.|..|.:|.:||::.|:|:..:.|  .::|.|.||...||.            |......
plant   205 FVGKSVLCAAVKSQNLDILTAVLESDSDLVESRDEDGRTPLATAASIGYDIGVQHMLTRFASSTQ 269

  Fly   291 EAFIERPE-----------------LMSLEEQITALELL---GATYANDKIKYDVNKAYGYLLRA 335
            .|:|:..:                 .:.|:.....:|:|   |....:...|....:|.|||||.
plant   270 VAYIKNEDGSFPIHSACSARCTSALKVILKHHPDTIEMLNSQGQNVLHVAAKSGNARAVGYLLRK 334

  Fly   336 MQLR-------------------YSNPRGVI----RKRV-------------------QPTVPAY 358
            ..::                   .|:|:.|.    .:||                   ..|:|:.
plant   335 SDVKRLINEQDIEGNTPLHLASSNSHPKVVSLFIHDRRVDLKILNYKGFTALDAAEDHMATIPSL 399

  Fly   359 DNWL--------ETENLPELYA------------IKLNHHSIHMESLAIRERI------------ 391
            ..||        .|...|.::.            :.|..|...:.:|.:...:
plant   400 QEWLIWMALVAAGTTRAPRVHLRADIPGLTTDEDLILKIHKDRVNTLLVVATLVATMAFAAGLSV 464

  Fly   392 -LGRNNPELPQAI-------IYRGAVMADQGRFYQCQV-----LWNYAIDLR-MRNNVSVDRDLL 442
             ||.|:.|....:       .:...|:.:....|...:     :.....||: |.........||
plant   465 PLGYNSTEFKSNVKHSYEESAFHAFVICNSIAVYTAVISTVALIGTQLADLKCMLTTFKFIVPLL 529

  Fly   443 RFAQLFAQILRVENHNLTLDH----------------------VLP-------VLAKCQQEIENN 478
            .|:.:...:..|....|.|.|                      ::|       .|::....:..|
plant   530 GFSIIAMSLAFVAGLYLVLGHHYWLAIFVLASGGFYLMALLLLIIPYASPYTFTLSRSLNSLVQN 594

  Fly   479 KFK-------------------IKEAKPNACPSLWQDQNNQNCITALYLIKIVTHLARRKKDQNI 524
            ..|                   ||..:.|.|     .|.|         |.:.:.:..||...|
plant   595 MSKEDVDSVNQLVPAPTEELALIKAIQVNRC-----IQGN---------IGVTSMMVPRKHTHN- 644

  Fly   525 DEEHIQQLFLVVRKFIQNDTRLQDGQTLLHIAVNGVMPVDEFYTNE----MCRFPCY 577
                .:...||.|:  ||::    |.|.|.||.....|...|..|.    :|.|.|:
plant   645 ----FRVPVLVARQ--QNNS----GLTALDIAELNPNPTTSFERNRLRVWLCVFSCF 691

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fem-1	NP_611508.1	ANK	61..196	CDD:238125	28/115 (24%)
		ANK repeat	103..129	CDD:293786	8/25 (32%)
		Ank_2	105..206	CDD:289560	27/117 (23%)
		ANK	142..262	CDD:238125	33/154 (21%)
		ANK repeat	142..173	CDD:293786	11/30 (37%)
		ANK repeat	178..206	CDD:293786	4/29 (14%)
		Ank_2	180..266	CDD:289560	23/120 (19%)
		ANK repeat	208..239	CDD:293786	11/63 (17%)
		ANK repeat	241..266	CDD:293786	8/24 (33%)
		Ank_4	244..294	CDD:290365	16/63 (25%)
		ANK	548..685	CDD:238125	11/34 (32%)
		ANK repeat	548..594	CDD:293786	11/34 (32%)
		ANK repeat	596..636	CDD:293786
AT4G03490	NP_001328102.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2399
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050