DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fem-1 and LOC110440003

DIOPT Version :9

Sequence 1:	NP_611508.1	Gene:	Fem-1 / 37344	FlyBaseID:	FBgn0034542	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	XP_021334017.1	Gene:	LOC110440003 / 110440003	-ID:	-	Length:	289	Species:	Danio rerio

Alignment Length:	192	Identity:	63/192 - (32%)
Similarity:	106/192 - (55%)	Gaps:	24/192 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 AARSGQMLSFVEILNSVSCRAVQTHLVNTNFDQPDGQSL---------TPLTMAAMMGNVKFVKT 119
            |||.|::            :.:|..|:|.:   |:.::.         |||.:||..|::..|..
Zfish    10 AARDGKL------------KLMQKLLINKS---PEERAALAEERTEGGTPLLIAARYGHLPVVHF 59

  Fly   120 LLSHYDVDLDRECNVIYDGMVVYGATALWVAAGMGHLQIVKMLVQAGAAINHNTKAQSSPLRAAC 184
            ||.....:::...:|.:||..:.||..||.|:..|||.:||.|::.||::|:.|...|:||||||
Zfish    60 LLERCGANVELGGSVNFDGETIEGAPPLWAASAAGHLPVVKALLEHGASVNNTTLTNSTPLRAAC 124

  Fly   185 YEGRLDIVEFLIDNGADVNATNLFNNNTLMIAAYKGHHLVVKTLLQNGSRANDQALCGATAL 246
            ::|.|:||.:|:::.||:...|...:..|||:.||||..:.:.||:.|:..|.:::.|...|
Zfish   125 FDGHLEIVRYLVEHQADLEVANRHGHTCLMISCYKGHREIAQFLLEKGADVNRRSVKGGVLL 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fem-1	NP_611508.1	ANK	61..196	CDD:238125	46/140 (33%)
		ANK repeat	103..129	CDD:293786	9/25 (36%)
		Ank_2	105..206	CDD:289560	39/100 (39%)
		ANK	142..262	CDD:238125	43/105 (41%)
		ANK repeat	142..173	CDD:293786	14/30 (47%)
		ANK repeat	178..206	CDD:293786	13/27 (48%)
		Ank_2	180..266	CDD:289560	26/67 (39%)
		ANK repeat	208..239	CDD:293786	11/30 (37%)
		ANK repeat	241..266	CDD:293786	2/6 (33%)
		Ank_4	244..294	CDD:290365	1/3 (33%)
		ANK	548..685	CDD:238125
		ANK repeat	548..594	CDD:293786
		ANK repeat	596..636	CDD:293786
LOC110440003	XP_021334017.1	Ank_2	<6..68	CDD:330894	17/72 (24%)
		ANK	40..169	CDD:238125	49/128 (38%)
		ANK repeat	40..75	CDD:293786	9/34 (26%)
		ANK repeat	82..113	CDD:293786	14/30 (47%)
		ANK repeat	115..146	CDD:293786	14/30 (47%)
		ANK repeat	148..178	CDD:293786	11/29 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D133963at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010