DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrt and Islr

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_001119772.1 Gene:Islr / 686539 RGDID:1596359 Length:428 Species:Rattus norvegicus


Alignment Length:386 Identity:95/386 - (24%)
Similarity:150/386 - (38%) Gaps:80/386 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   343 PGM-RNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGI 406
            ||. .|:.:|:|:.|.:..:...:......|.||.|.||:|..:...|...||.|.|||||:|.|
  Rat    46 PGFPANVTTLSLSANRLPVLLEGSFREVPLLQSLWLAHNEIRSVAVGALAPLGHLKSLDLSHNLI 110

  Fly   407 VAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESL 471
            ...:.:.|.:||.|.:|.:..|.|..:..|....|.:||.|:|..|.:..:|.........|..|
  Rat   111 SEFAWSDLHNLSALQLLKMDSNELAFIPRDAFRSLHALRSLQLNHNRLHALAEGTFAPLTSLSHL 175

  Fly   472 QMQENPLSCDCSIRPFAEWLQESQLHSSLS------ASCVTPPRLEGAPLLQVPVETLSCDMDNV 530
            |:..||..|.|.|..|..|    .|.:::|      .:|.:|..|:|.||.::|  .|.|...:|
  Rat   176 QINHNPFDCTCGIVWFKTW----ALATAVSIPEQDNIACTSPHVLKGTPLSRLP--PLPCSAPSV 234

  Fly   531 EKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLI--LTWLLNLSKKDYMCDAIFV 593
            :..           .:|:|..  .:|....:| .||...|...:  |.|                
  Rat   235 QLS-----------YQPSQDG--AELRPGFVL-ALHCDVDGQPVPQLHW---------------- 269

  Fly   594 YKEEHIN-----------EILIDNSPIHCESKVVNGQNTV------SVIVPDSSSLEIGESYRFC 641
                ||:           .:..|..|:. .:...:||...      |:::||...||.| :|. |
  Rat   270 ----HIHTPGGTVEIASPNVGTDGRPLP-GALAASGQPRFQAFANGSLLIPDFGKLEEG-TYS-C 327

  Fly   642 LVMIQEQKPDSELNIGCSNITRLERSSPGAVPVSRQYQRRP------YYNANELKPEVVHD 696
            |...:....:|.:|:..:.     ....|...|.|::..:.      |...||::|....|
  Rat   328 LATNELGSAESSVNVALAT-----PGEGGEDAVGRKFHGKTVEGKGCYTVDNEVQPSGPED 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064
leucine-rich repeat 179..199 CDD:275378
leucine-rich repeat 200..223 CDD:275380
leucine-rich repeat 225..248 CDD:275380
LRR_8 249..307 CDD:290566
leucine-rich repeat 249..272 CDD:275380
LRR_RI <270..479 CDD:238064 44/136 (32%)
leucine-rich repeat 273..296 CDD:275380
leucine-rich repeat 297..322 CDD:275380
LRR_8 322..382 CDD:290566 12/39 (31%)
leucine-rich repeat 323..347 CDD:275380 2/4 (50%)
leucine-rich repeat 348..371 CDD:275380 3/22 (14%)
LRR_8 370..428 CDD:290566 23/57 (40%)
leucine-rich repeat 372..395 CDD:275380 9/22 (41%)
leucine-rich repeat 396..419 CDD:275380 10/22 (45%)
LRR_8 418..478 CDD:290566 17/59 (29%)
leucine-rich repeat 420..443 CDD:275380 6/22 (27%)
leucine-rich repeat 444..467 CDD:275380 6/22 (27%)
LRRCT 476..526 CDD:214507 17/55 (31%)
IslrNP_001119772.1 leucine-rich repeat 32..51 CDD:275380 2/4 (50%)
LRR_8 51..110 CDD:404697 21/58 (36%)
leucine-rich repeat 52..75 CDD:275380 3/22 (14%)
leucine-rich repeat 76..99 CDD:275380 9/22 (41%)
LRR_8 99..158 CDD:404697 22/58 (38%)
leucine-rich repeat 100..123 CDD:275380 10/22 (45%)
leucine-rich repeat 124..147 CDD:275380 6/22 (27%)
leucine-rich repeat 148..171 CDD:275380 6/22 (27%)
PCC 153..>227 CDD:188093 22/79 (28%)
Ig 239..343 CDD:416386 26/129 (20%)
Ig strand C 265..287 CDD:409353 4/41 (10%)
Ig strand C' 288..290 CDD:409353 1/1 (100%)
Ig strand D 304..307 CDD:409353 0/2 (0%)
Ig strand E 310..316 CDD:409353 1/5 (20%)
Ig strand F 323..331 CDD:409353 4/9 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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