DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrt and Lrit2

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_001178867.1 Gene:Lrit2 / 498594 RGDID:1564668 Length:549 Species:Rattus norvegicus


Alignment Length:447 Identity:95/447 - (21%)
Similarity:162/447 - (36%) Gaps:147/447 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   310 YAQSLRSLSQCL---------SLRQLDLQANNLNGPLSEQTLP-----GMRNLESLNLNRNLIKS 360
            :.:||:.:|..|         .|:|:.::    ..||.|  ||     .:..||.|.||.|.:..
  Rat    35 FGRSLQCMSMSLGKIPDNFPEGLKQVRIE----KSPLFE--LPQGVFTNLNTLEYLWLNFNNVTV 93

  Fly   361 IQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDL 425
            |...||.:..:|..|.|..|::..:...||.....|..|||.:|.|.|:...:||.|:.||.||:
  Rat    94 IHLGALEDLPQLRELRLEGNRLRSVPWTAFRATPFLRVLDLKHNRIDALPELALQFLANLTYLDI 158

  Fly   426 THNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEW 490
            :.|.|..::..:....|:.::.:..|....|::...         |.:..||..|||.:...|::
  Rat   159 SSNRLTVVSKGVFLNWPAYQKRQQLGCGAEILSHMV---------LSLHNNPWLCDCRLTGLAQF 214

  Fly   491 LQE----------------------SQLHSSLSASCVTPPRLEGAPLLQVPVE-----TLSC--- 525
            ::.                      ..||.:....|:.|  :...|...|.::     ||.|   
  Rat   215 VKSVGPPFILVNSYLICQGPVSKAGQLLHETELGDCMKP--IISTPSANVSIQVGKNVTLQCLAQ 277

  Fly   526 --DMDNVE-KDNANIMQHLETLAKPNQTSPIKDLSEEII-------------------------- 561
              ....:| |...:..:..:.||.|.....|  ||:.:|                          
  Rat   278 ASPSPTIEWKYPLSTWRKFDVLALPVAEGFI--LSQLVIPAAQLVDGTNYTCMASNSIGRSSLVI 340

  Fly   562 ------------LHELHFSTD--------------YGLILTWL--LNLSKKDYMCDAIFVYKEEH 598
                        ||.|..|::              :|::|.||  .||:.:.:.  .:::..:|.
  Rat   341 TLYVQPAQATPGLHSLSTSSEGSSYVDLRVVKQTVHGILLEWLTVTNLAGEQWF--TLYIASDEA 403

  Fly   599 INEILIDNSPIHCESKVVN---GQNTVSV--IVPDSSSLEIGESYRFCLVMIQEQKP 650
            :            |.|||:   |.||.:|  ::|       ...|:.|| .::.|.|
  Rat   404 L------------EKKVVHIGPGINTYAVDDLLP-------ATKYKACL-GLRNQPP 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064 6/32 (19%)
leucine-rich repeat 179..199 CDD:275378
leucine-rich repeat 200..223 CDD:275380
leucine-rich repeat 225..248 CDD:275380
LRR_8 249..307 CDD:290566
leucine-rich repeat 249..272 CDD:275380
LRR_RI <270..479 CDD:238064 48/182 (26%)
leucine-rich repeat 273..296 CDD:275380
leucine-rich repeat 297..322 CDD:275380 4/20 (20%)
LRR_8 322..382 CDD:290566 20/64 (31%)
leucine-rich repeat 323..347 CDD:275380 7/28 (25%)
leucine-rich repeat 348..371 CDD:275380 9/22 (41%)
LRR_8 370..428 CDD:290566 20/57 (35%)
leucine-rich repeat 372..395 CDD:275380 6/22 (27%)
leucine-rich repeat 396..419 CDD:275380 10/22 (45%)
LRR_8 418..478 CDD:290566 11/59 (19%)
leucine-rich repeat 420..443 CDD:275380 6/22 (27%)
leucine-rich repeat 444..467 CDD:275380 2/22 (9%)
LRRCT 476..526 CDD:214507 15/81 (19%)
Lrit2NP_001178867.1 LRR_8 56..115 CDD:290566 20/64 (31%)
leucine-rich repeat 57..80 CDD:275378 7/28 (25%)
LRR_4 81..119 CDD:289563 13/37 (35%)
leucine-rich repeat 81..104 CDD:275378 9/22 (41%)
LRR_8 103..163 CDD:290566 21/59 (36%)
leucine-rich repeat 105..128 CDD:275378 6/22 (27%)
LRR_4 129..164 CDD:289563 15/34 (44%)
leucine-rich repeat 129..152 CDD:275378 10/22 (45%)
leucine-rich repeat 153..164 CDD:275378 5/10 (50%)
leucine-rich repeat 177..204 CDD:275378 5/35 (14%)
TPKR_C2 200..243 CDD:301599 6/42 (14%)
I-set 253..344 CDD:254352 15/94 (16%)
Ig 270..341 CDD:143165 12/72 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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