DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrt and kek6

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster


Alignment Length:612 Identity:119/612 - (19%)
Similarity:212/612 - (34%) Gaps:221/612 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 LQALGLPGNALMSVPWNALSTLSA--LERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSIS 287
            ||.|.|..|.:..:.....|||..  |:|:.|..::::.:....|..|..||.::||:|::..:.
  Fly    71 LQVLVLNDNHIPYLNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLD 135

  Fly   288 QRTFVNLRKLEVLKLGGN---RLGDYAQSLRSLSQCLSLRQLDLQANNLNGPLSEQTLPGMRNLE 349
            :.||:...:|.:|.|.||   ||..|                              ..|.:.:|.
  Fly   136 KDTFMGNDRLRILYLNGNPLKRLAAY------------------------------QFPILPHLR 170

  Fly   350 SLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASL 414
            :|:::..||..|...:|||.:.|..|:|::|.::.|.::.|                        
  Fly   171 TLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVF------------------------ 211

  Fly   415 QHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLS 479
            ||::                                                .|::|.::|||..
  Fly   212 QHMA------------------------------------------------NLKTLSLEENPWQ 228

  Fly   480 CDCSIRPFAEWLQESQLHSSLSASCVTPP------------RLEGAP----------LLQVPV-- 520
            |:|.:|.|..|...|:| ||:|..|..||            .|.|.|          :..:.:  
  Fly   229 CNCKLRKFRGWYVNSRL-SSVSLVCKGPPAQKDRTWDSVDDELFGCPPRVEIFNNEEVQNIDIGS 292

  Fly   521 -ETLSC------------DMDNVEKDNANIMQHLETLAKP------------------------- 547
             .|.||            :::....||.|::...|::|..                         
  Fly   293 NTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESESIASDKLWSNLTVFNVTSLDAGTYACTGSN 357

  Fly   548 ---NQTSPIKDLSEEIILHELHFSTD----YGLIL------TWLLNLSKKDYMCDAIFVYKEEHI 599
               :.|..|.....||:.|.|..:.:    :|||:      ..|:::|....:|... ..:..|.
  Fly   358 SIGSMTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFVVCLCKRT-TRQHRHA 421

  Fly   600 NEILIDNSPI--HCESKVVNGQNTVSVIVPDSSSLEIGESYRFCLVMIQEQKPDSELNIGCS--- 659
            |:..:.:|..  ..|.|:::...|       :::.:.|:||.     |..|.....:|.|.|   
  Fly   422 NKAGVKSSVSFNDQEKKLLDSSVT-------TTTNDRGDSYG-----IDNQPTSIGMNKGDSAGM 474

  Fly   660 -----NITRLERSSPGAVPVSRQYQRRPYYNANELKPEVVHDAGEDYQVNQRRFNSVVGSQPQQT 719
                 .|..:|....|::.|.:|.|::          :|....|...|:.|.: :|..|.....|
  Fly   475 GFNQIEIHAVESHRHGSMLVQQQPQQQ----------QVAGGGGMRQQLMQVK-DSTCGMMSVPT 528

  Fly   720 QQSTLLHSYTVIDSLNKSFLPGLGLGV 746
            ..:...||:..  .:::.|  .|.:||
  Fly   529 SMAGHAHSHPA--QISEEF--PLNVGV 551

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064 28/113 (25%)
leucine-rich repeat 179..199 CDD:275378
leucine-rich repeat 200..223 CDD:275380
leucine-rich repeat 225..248 CDD:275380 8/22 (36%)
LRR_8 249..307 CDD:290566 17/60 (28%)
leucine-rich repeat 249..272 CDD:275380 5/22 (23%)
LRR_RI <270..479 CDD:238064 38/211 (18%)
leucine-rich repeat 273..296 CDD:275380 7/22 (32%)
leucine-rich repeat 297..322 CDD:275380 8/27 (30%)
LRR_8 322..382 CDD:290566 13/59 (22%)
leucine-rich repeat 323..347 CDD:275380 1/23 (4%)
leucine-rich repeat 348..371 CDD:275380 8/22 (36%)
LRR_8 370..428 CDD:290566 8/57 (14%)
leucine-rich repeat 372..395 CDD:275380 6/22 (27%)
leucine-rich repeat 396..419 CDD:275380 2/22 (9%)
LRR_8 418..478 CDD:290566 4/59 (7%)
leucine-rich repeat 420..443 CDD:275380 0/22 (0%)
leucine-rich repeat 444..467 CDD:275380 0/22 (0%)
LRRCT 476..526 CDD:214507 21/86 (24%)
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 8/24 (33%)
LRR_8 96..155 CDD:290566 17/58 (29%)
leucine-rich repeat 97..120 CDD:275380 5/22 (23%)
leucine-rich repeat 121..144 CDD:275380 7/22 (32%)
LRR_4 144..186 CDD:289563 14/71 (20%)
leucine-rich repeat 145..168 CDD:275380 9/52 (17%)
leucine-rich repeat 169..216 CDD:275380 16/118 (14%)
LRRCT 225..274 CDD:214507 17/49 (35%)
Ig 295..367 CDD:143165 9/71 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24366
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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