DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lrt and Lgi4

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_955793.1 Gene:Lgi4 / 361549 RGDID:735035 Length:537 Species:Rattus norvegicus


Alignment Length:361 Identity:79/361 - (21%)
Similarity:125/361 - (34%) Gaps:95/361 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   348 LESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSA 412
            |.||:|.|..:..::..:......|..|....|...|::..||.||..|..|.:..|.|.:||..
  Rat    54 LLSLSLVRMGVSRLKAGSFLKMPSLHLLLFTSNTFSVIEGDAFIGLSYLQYLFIEDNKIGSISKN 118

  Fly   413 SLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENP 477
            :|:.|..||.|.|.:|.|.||...|...|.:|..:.|.|                        ||
  Rat   119 ALRGLRSLTHLSLANNHLEALPRFLFQGLETLTHVDLRG------------------------NP 159

  Fly   478 LSCDCSIRPFAEWLQESQLHSSL-SASCVTPPRLEGAPLLQVPVETLSCDMDNVEKDNANIMQHL 541
            ..|||.:....:|:  ..:::|: :.:|..|..|....|..:..:...|        .|..:..|
  Rat   160 FQCDCRVLWLLQWM--PMVNASVGTGACAGPSALAQIQLNHLDPKKFKC--------KATELSWL 214

  Fly   542 ETLAKPNQTSPIKDLSEEIILHELHFSTDYG--LILTWLLNLSKKDYMCDAIFVYKEEHINEILI 604
            :|:.:  ....::..|.:...|.:......|  |||.|..:|.:          ::.|   |.|.
  Rat   215 QTVGE--SALSVESFSYQGEPHMVLAQPFAGRCLILVWDYSLQR----------FRSE---EELS 264

  Fly   605 DNSPIHCESKVVNGQ------------------------NTVSVIVP-------DSSSLEI-GES 637
            ..|.:.|:..|:..:                        ..|.|:.|       |:..|.: |:.
  Rat   265 APSVVSCKPLVLGPRLFILAARLWGGSQLWSRSSPDLRLTPVQVLAPQRLLRPNDAELLWLDGQP 329

  Fly   638 YRFCLVMIQEQKPDSELNIGCSNITRLERSSPGAVP 673
               |.|:....|..|        .|.|.|..||..|
  Rat   330 ---CFVVADASKAGS--------TTLLCRDGPGFYP 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064
leucine-rich repeat 179..199 CDD:275378
leucine-rich repeat 200..223 CDD:275380
leucine-rich repeat 225..248 CDD:275380
LRR_8 249..307 CDD:290566
leucine-rich repeat 249..272 CDD:275380
LRR_RI <270..479 CDD:238064 36/130 (28%)
leucine-rich repeat 273..296 CDD:275380
leucine-rich repeat 297..322 CDD:275380
LRR_8 322..382 CDD:290566 8/33 (24%)
leucine-rich repeat 323..347 CDD:275380
leucine-rich repeat 348..371 CDD:275380 5/22 (23%)
LRR_8 370..428 CDD:290566 20/57 (35%)
leucine-rich repeat 372..395 CDD:275380 8/22 (36%)
leucine-rich repeat 396..419 CDD:275380 8/22 (36%)
LRR_8 418..478 CDD:290566 14/59 (24%)
leucine-rich repeat 420..443 CDD:275380 10/22 (45%)
leucine-rich repeat 444..467 CDD:275380 3/22 (14%)
LRRCT 476..526 CDD:214507 11/50 (22%)
Lgi4NP_955793.1 leucine-rich repeat 54..77 CDD:275378 5/22 (23%)
LRR_8 76..136 CDD:290566 21/59 (36%)
leucine-rich repeat 78..101 CDD:275378 8/22 (36%)
LRR_4 102..140 CDD:289563 15/37 (41%)
leucine-rich repeat 102..125 CDD:275378 8/22 (36%)
leucine-rich repeat 126..149 CDD:275378 10/22 (45%)
leucine-rich repeat 150..162 CDD:275378 5/35 (14%)
LRRCT 158..207 CDD:214507 12/58 (21%)
EPTP <220..251 CDD:281697 6/30 (20%)
EPTP 351..392 CDD:281697 2/4 (50%)
EPTP 396..438 CDD:281697
EPTP 441..482 CDD:281697
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.