DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lrt and CG14762

DIOPT Version :9

Sequence 1:	NP_001286640.1	Gene:	Lrt / 37342	FlyBaseID:	FBgn0034540	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_001246198.1	Gene:	CG14762 / 35768	FlyBaseID:	FBgn0033250	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	93/356 - (26%)
Similarity:	165/356 - (46%)	Gaps:	55/356 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 NAELECGCDLPHTLRCNIDLHGMMLLADRLRTSPYSISLLDCSLRNVTFLSDAKIFDNVSLHGLV 204
            ||....|..|   .:.::.|:.|..:..:.....:.:.:|:.:...:|.:.:.......:|..|.
  Fly   122 NALSSLGAGL---TQLDVSLNQMKTVPSQALQHLFHLLILNLNHNKITVIHNNAFEGLETLEILT 183

  Fly   205 ISSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVG 269
            :...:|.::...||.|:...::.|.|.||.|.::|..|||.||.|::|::..|||:.:...||.|
  Fly   184 LYENKITQIDPEAFRGLEDHIKRLNLGGNDLTNIPQKALSILSTLKKLEIQENKIRTISEGDFEG 248

  Fly   270 LTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQCLSLRQLDLQANNLN 334
            |.||..|.|::|.|:::....|.:|..|..|:|.||::
  Fly   249 LQSLDSLILAHNMITTVPANVFSHLTLLNSLELEGNKI--------------------------- 286

  Fly   335 GPLSEQTLPGM-RNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLG-ALD 397
            ..:.:....|: .||:.|.|..|.|.:|.::||....||..|.||:|.|:||.:.||.|.| :|.
  Fly   287 SVIDKDAFKGLEENLQYLRLGDNQIHTIPSEALRPLHRLRHLDLRNNNINVLAEDAFTGFGDSLT 351

  Fly   398 SLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAM 462
            .|:|..|.|..:.|...::|:.|..|:|.:|.|:.:..|::.|:  :..||:
  Fly   352 FLNLQKNDIKVLPSLLFENLNSLETLNLQNNKLQRIPQDIMEPV--IDTLRI------------- 401

  Fly   463 DGARELESLQMQENPLSCDCSIRPFAEWLQE 493
                    :.:.:|||:|.|.:..|.:.|::
  Fly   402 --------IDITDNPLNCSCELTWFPKLLED 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lrt	NP_001286640.1	LRR_RI	<151..334	CDD:238064	43/182 (24%)
		leucine-rich repeat	179..199	CDD:275378	2/19 (11%)
		leucine-rich repeat	200..223	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..248	CDD:275380	10/22 (45%)
		LRR_8	249..307	CDD:290566	22/57 (39%)
		leucine-rich repeat	249..272	CDD:275380	9/22 (41%)
		LRR_RI	<270..479	CDD:238064	55/210 (26%)
		leucine-rich repeat	273..296	CDD:275380	7/22 (32%)
		leucine-rich repeat	297..322	CDD:275380	5/24 (21%)
		LRR_8	322..382	CDD:290566	16/60 (27%)
		leucine-rich repeat	323..347	CDD:275380	1/24 (4%)
		leucine-rich repeat	348..371	CDD:275380	8/22 (36%)
		LRR_8	370..428	CDD:290566	23/58 (40%)
		leucine-rich repeat	372..395	CDD:275380	12/23 (52%)
		leucine-rich repeat	396..419	CDD:275380	7/22 (32%)
		LRR_8	418..478	CDD:290566	10/59 (17%)
		leucine-rich repeat	420..443	CDD:275380	7/22 (32%)
		leucine-rich repeat	444..467	CDD:275380	2/22 (9%)
		LRRCT	476..526	CDD:214507	7/18 (39%)
CG14762	NP_001246198.1	leucine-rich repeat	85..105	CDD:275380
		LRR_RI	93..384	CDD:238064	81/291 (28%)
		leucine-rich repeat	107..129	CDD:275380	2/6 (33%)
		leucine-rich repeat	131..154	CDD:275380	3/25 (12%)
		LRR_8	154..214	CDD:290566	12/59 (20%)
		leucine-rich repeat	155..178	CDD:275380	2/22 (9%)
		leucine-rich repeat	179..203	CDD:275380	6/23 (26%)
		leucine-rich repeat	204..227	CDD:275380	10/22 (45%)
		LRR_8	226..286	CDD:290566	23/59 (39%)
		leucine-rich repeat	228..251	CDD:275380	9/22 (41%)
		leucine-rich repeat	252..275	CDD:275380	7/22 (32%)
		LRR_8	276..335	CDD:290566	21/85 (25%)
		leucine-rich repeat	276..300	CDD:275380	6/50 (12%)
		leucine-rich repeat	301..324	CDD:275380	8/22 (36%)
		leucine-rich repeat	325..349	CDD:275380	12/23 (52%)
		LRR_8	349..409	CDD:290566	17/82 (21%)
		leucine-rich repeat	350..373	CDD:275380	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910