DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lrt and haf

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster


Alignment Length:395 Identity:126/395 - (31%)
Similarity:175/395 - (44%) Gaps:49/395 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 ELECGCDLPHTLRCNIDLHGMM-LLADRLRTSPYSISLLDCSLRNVTFLSDAKIFDNVSLHGLVI 205
            ||...||       .:|...:: .:....|..|  :.||..:...::.|.|| :|.|:|||.|.:
  Fly    57 ELSVQCD-------QVDFSQLLAAMNTHARLKP--VDLLYVNNSTISELPDA-VFSNLSLHNLQL 111

  Fly   206 SSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGL 270
            ||..|:|:...||.|....|:.|.|..|.|..||..||..|..|..|||:.|::..:....||||
  Fly   112 SSCGIQRIATGAFKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGL 176

  Fly   271 TSLVYLELSNNQISSISQRTFVNL-RKLEVLKLGGNRLGDYAQSLRSLSQCLSLRQLDLQAN--- 331
            |.|..|:|::|.: :::...|..| :.|:.|.|.|.:.....:|:|.|.   ||..|||..|   
  Fly   177 TKLSTLKLNDNNV-TLASNAFRGLEQSLKNLNLKGTKQRKVPESIRGLK---SLAFLDLSQNGIK 237

  Fly   332 NLNGPLSEQTLPGMRNLESLNLNRNLIKSIQNKALANFSR-LVSLSLRHNQIDVLQDHAFFGLGA 395
            .|.|....:...|:..|.:|||.||||:||...|.|...: |.||||.:|.:      |.|.:||
  Fly   238 ELPGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRKTLSSLSLLNNLL------AEFPIGA 296

  Fly   396 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARN 460
            :.|                  |..|.|||:..|.|.:|........|.:..|.|.||.:|.|...
  Fly   297 VHS------------------LKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGNPLSSVPEG 343

  Fly   461 AMDGAR-ELESLQMQENPLSCDCSIRPFAEWLQESQLHSSLSAS----CVTPPRLEGAPLLQVPV 520
            |..... .|..|.:....|.|||.:|..|||::...|..:....    |.||||........:..
  Fly   344 AFAHLNATLRGLSLGGRFLHCDCKLRWVAEWIRNGDLQVTSRERNPQFCGTPPRFRDRGFYSIQP 408

  Fly   521 ETLSC 525
            |.|||
  Fly   409 EELSC 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064 60/187 (32%)
leucine-rich repeat 179..199 CDD:275378 6/19 (32%)
leucine-rich repeat 200..223 CDD:275380 10/22 (45%)
leucine-rich repeat 225..248 CDD:275380 10/22 (45%)
LRR_8 249..307 CDD:290566 20/58 (34%)
leucine-rich repeat 249..272 CDD:275380 9/22 (41%)
LRR_RI <270..479 CDD:238064 65/214 (30%)
leucine-rich repeat 273..296 CDD:275380 6/23 (26%)
leucine-rich repeat 297..322 CDD:275380 7/24 (29%)
LRR_8 322..382 CDD:290566 27/63 (43%)
leucine-rich repeat 323..347 CDD:275380 8/26 (31%)
leucine-rich repeat 348..371 CDD:275380 12/22 (55%)
LRR_8 370..428 CDD:290566 16/58 (28%)
leucine-rich repeat 372..395 CDD:275380 8/22 (36%)
leucine-rich repeat 396..419 CDD:275380 2/22 (9%)
LRR_8 418..478 CDD:290566 17/60 (28%)
leucine-rich repeat 420..443 CDD:275380 7/22 (32%)
leucine-rich repeat 444..467 CDD:275380 7/23 (30%)
LRRCT 476..526 CDD:214507 18/54 (33%)
hafNP_001356954.1 LRR <52..>252 CDD:227223 67/208 (32%)
leucine-rich repeat 86..105 CDD:275380 6/19 (32%)
leucine-rich repeat 106..129 CDD:275380 10/22 (45%)
LRR_8 131..189 CDD:338972 24/57 (42%)
leucine-rich repeat 131..154 CDD:275380 10/22 (45%)
leucine-rich repeat 155..178 CDD:275380 9/22 (41%)
leucine-rich repeat 179..202 CDD:275380 6/23 (26%)
leucine-rich repeat 203..225 CDD:275380 7/24 (29%)
leucine-rich repeat 226..253 CDD:275380 8/26 (31%)
LRR_8 254..337 CDD:338972 36/106 (34%)
leucine-rich repeat 254..302 CDD:275380 24/71 (34%)
leucine-rich repeat 303..326 CDD:275380 7/22 (32%)
leucine-rich repeat 327..350 CDD:275380 7/22 (32%)
PCC 332..>413 CDD:188093 24/80 (30%)
PRK10927 <1061..>1097 CDD:236797
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24366
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.