Protein Alignment Lrt and Islr

DIOPT Version :9

• Sequence 1: NP_001286640.1
• Gene: Lrt / 37342
• FlyBaseID: FBgn0034540
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: XP_006511267.1
• Gene: Islr / 26968
• MGIID: 1349645
• Length: 436
• Species: Mus musculus
• Alignment Length: 360
• Identity: 88/360 - (24%)
• Similarity: 134/360 - (37%)
• Gaps: 99/360 - (27%)

  Fly   343 PGM-RNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGI 406
            ||. .|:.:|:|:.|.:..:...|......|.||.|.||:|..:...|...|..|.|||||:|.:
Mouse    54 PGFPANVTTLSLSANRLPGLPEGAFREVPLLQSLWLAHNEIRSVAIGALAPLSHLKSLDLSHNLL 118

  Fly   407 VAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESL 471
            ...:.:.|.:||.|.:|.:..|.|..:..|..:.|.:||.|:|..|.:..:|.........|..|
Mouse   119 SEFAWSDLHNLSALQLLKMDSNELAFIPRDAFSSLSALRSLQLNHNRLHALAEGTFAPLTALSHL 183

  Fly   472 QMQENPLSCDCSIRPFAEWLQESQLHSSLS------ASCVTPPRLEGAPLLQVPVETLSCDMDNV 530
            |:.:||..|.|.|..|..|    .|.|::|      .:|.||..|:|.||.::|  .|.|...:|
Mouse   184 QINDNPFDCTCGIVWFKTW----ALASAVSIPEQDNIACTTPHVLKGIPLGRLP--PLPCSAPSV 242

  Fly   531 EKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLILTWLLNLSKKDYMCDAIFVYK 595
            :..           .:|:|..  .:|....:| .||                     ||
Mouse   243 QLS-----------YQPSQDG--AELRPGFVL-ALH---------------------CD------ 266

  Fly   596 EEHINEILIDNSPI---HCESKVVNGQNTVSVIVPDSSSLEIGESYRFCLVMIQEQKPDSELNIG 657
                    :|..|:   |.......|  ||.:..|                           |:|
Mouse   267 --------VDGQPVPQLHWHIHTPGG--TVEIASP---------------------------NVG 294

  Fly   658 CSNITRLERSSPGAVPVSRQYQRRPYYNANELKPE 692
            ...     |:.|||:..|.|.:.:.:.|.:.|.|:
Mouse   295 TDG-----RALPGALATSGQPRFQAFANGSLLIPD 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lrt	NP_001286640.1	LRR_RI	<151..334	CDD:238064
		leucine-rich repeat	179..199	CDD:275378
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	225..248	CDD:275380
		LRR_8	249..307	CDD:290566
		leucine-rich repeat	249..272	CDD:275380
		LRR_RI	<270..479	CDD:238064	43/136 (32%)
		leucine-rich repeat	273..296	CDD:275380
		leucine-rich repeat	297..322	CDD:275380
		LRR_8	322..382	CDD:290566	13/39 (33%)
		leucine-rich repeat	323..347	CDD:275380	2/4 (50%)
		leucine-rich repeat	348..371	CDD:275380	4/22 (18%)
		LRR_8	370..428	CDD:290566	21/57 (37%)
		leucine-rich repeat	372..395	CDD:275380	9/22 (41%)
		leucine-rich repeat	396..419	CDD:275380	9/22 (41%)
		LRR_8	418..478	CDD:290566	17/59 (29%)
		leucine-rich repeat	420..443	CDD:275380	6/22 (27%)
		leucine-rich repeat	444..467	CDD:275380	6/22 (27%)
		LRRCT	476..526	CDD:214507	19/55 (35%)
Islr	XP_006511267.1	leucine-rich repeat	40..59	CDD:275380	2/4 (50%)
		LRR_8	59..118	CDD:338972	21/58 (36%)
		leucine-rich repeat	60..83	CDD:275380	4/22 (18%)
		leucine-rich repeat	84..107	CDD:275380	9/22 (41%)
		LRR_8	107..166	CDD:338972	21/58 (36%)
		leucine-rich repeat	108..131	CDD:275380	9/22 (41%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..179	CDD:275380	6/22 (27%)
		PCC	161..>235	CDD:188093	24/79 (30%)
		Ig	263..349	CDD:319273	22/131 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100