DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrt and Lrit2

DIOPT Version :9

Sequence 1:NP_001286640.1 Gene:Lrt / 37342 FlyBaseID:FBgn0034540 Length:830 Species:Drosophila melanogaster
Sequence 2:NP_775594.1 Gene:Lrit2 / 239038 MGIID:2444885 Length:549 Species:Mus musculus


Alignment Length:551 Identity:114/551 - (20%)
Similarity:183/551 - (33%) Gaps:206/551 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   310 YAQSLRSLSQCL---------SLRQLDLQANNLNGP---LSEQTLPGMRNLESLNLNRNLIKSIQ 362
            :.:||:.:|..|         .|:|:.::    |.|   ||:.....|.:||.|.||.|.:..|.
Mouse    35 FGRSLQCMSMSLGKIPDNFPEELKQVRIE----NSPLFELSQGFFTNMSSLEYLWLNFNNVTVIH 95

  Fly   363 NKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTH 427
            ..||.:...|..|.|..|::..:...||.....|..|||.:|.|.::...:||.|:.|..||::.
Mouse    96 LGALEDLPELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNLIYLDISS 160

  Fly   428 NFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELES--LQMQENPLSCDCSIRPFAEW 490
            |.|..::..:....|:.::.:..|           .||..|.:  |.:..||..|||.:|..|::
Mouse   161 NRLTVVSKGVFLNWPAYQKRQQLG-----------CGAEFLSNMVLSLHNNPWLCDCRLRGLAQF 214

  Fly   491 LQE----------------------SQLHSSLSASCVTPPRLEGAPLLQVPVE-----TLSC--- 525
            ::.                      ..||.:....|:.|  ....|.:.|.::     ||.|   
Mouse   215 VKSVGPPFILVNSYLVCQGPVSKAGQLLHETELGVCMKP--TISTPSVNVTIQVGKNVTLQCFAQ 277

  Fly   526 ---DMDNVEKDNANIMQHLETLAKPNQTSPIKDLSEEIILHE----------------------- 564
               ......|...:..:..:.||.|        ::|.|||.:                       
Mouse   278 ASPSPTIAWKYPLSTWREFDVLASP--------IAEGIILSQLVIPAAQLVDGGNYTCMAFNSIG 334

  Fly   565 ------------------LHF-----------------STDYGLILTWL--LNLSKKDYMCDAIF 592
                              |||                 .|.:|::|.||  .||:::.:.  .::
Mouse   335 RSSLVILLYVQPAQAMPGLHFLSTSSEVSAYVDLRVVKQTVHGILLQWLTVTNLAEEQWF--TLY 397

  Fly   593 VYKEE-------H----INEILID---------------NSPIHCESKVVNGQNTVSVIVPDSSS 631
            :..:|       |    ||...:|               |.|      ...||..|.|...||..
Mouse   398 ITSDEALRKKVVHIGPGINTYAVDDLLPATKYKACLSLRNQP------PSQGQCVVFVTGKDSGG 456

  Fly   632 LEIGE-----SYRFCLVMIQEQKPDSELNIG---------------CSNITRLERSS---PGAVP 673
            ||..|     :...|.|::       .|.:|               |.....|.|.:   |.|||
Mouse   457 LEGREHLLHVTVVLCAVLL-------ALPVGAYVWVSQGPYNFSEWCWRRCPLHRKTLRCPQAVP 514

  Fly   674 VSRQYQRRPYYNANELK-PEVVHDAGEDYQV 703
            ..:.         |..| |..|::.||.::|
Mouse   515 QCKD---------NSFKDPSGVYEDGESHRV 536

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LrtNP_001286640.1 LRR_RI <151..334 CDD:238064 6/32 (19%)
leucine-rich repeat 179..199 CDD:275378
leucine-rich repeat 200..223 CDD:275380
leucine-rich repeat 225..248 CDD:275380
LRR_8 249..307 CDD:290566
leucine-rich repeat 249..272 CDD:275380
LRR_RI <270..479 CDD:238064 48/182 (26%)
leucine-rich repeat 273..296 CDD:275380
leucine-rich repeat 297..322 CDD:275380 4/20 (20%)
LRR_8 322..382 CDD:290566 20/62 (32%)
leucine-rich repeat 323..347 CDD:275380 7/26 (27%)
leucine-rich repeat 348..371 CDD:275380 9/22 (41%)
LRR_8 370..428 CDD:290566 18/57 (32%)
leucine-rich repeat 372..395 CDD:275380 6/22 (27%)
leucine-rich repeat 396..419 CDD:275380 9/22 (41%)
LRR_8 418..478 CDD:290566 12/61 (20%)
leucine-rich repeat 420..443 CDD:275380 5/22 (23%)
leucine-rich repeat 444..467 CDD:275380 3/22 (14%)
LRRCT 476..526 CDD:214507 16/82 (20%)
Lrit2NP_775594.1 LRR_8 56..115 CDD:290566 20/62 (32%)
leucine-rich repeat 57..80 CDD:275378 7/26 (27%)
LRR_4 80..119 CDD:289563 13/38 (34%)
leucine-rich repeat 81..104 CDD:275378 9/22 (41%)
LRR_8 103..163 CDD:290566 19/59 (32%)
leucine-rich repeat 105..128 CDD:275378 6/22 (27%)
LRR_4 129..164 CDD:289563 13/34 (38%)
leucine-rich repeat 129..152 CDD:275378 9/22 (41%)
leucine-rich repeat 153..164 CDD:275378 4/10 (40%)
leucine-rich repeat 193..204 CDD:275378 3/10 (30%)
TPKR_C2 200..243 CDD:301599 7/42 (17%)
I-set 253..344 CDD:254352 14/100 (14%)
Ig 266..345 CDD:299845 11/86 (13%)
fn3 367..441 CDD:278470 14/81 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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