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Protein Alignment Lrt and LGI3

DIOPT Version :10

Sequence 1:	NP_001286640.1	Gene:	Lrt / 37342	FlyBaseID:	FBgn0034540	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_644807.1	Gene:	LGI3 / 203190	HGNCID:	18711	Length:	548	Species:	Homo sapiens

Alignment Length:	512	Identity:	114/512 - (22%)
Similarity:	184/512 - (35%)	Gaps:	157/512 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   346 RNLESLNLNRNLIKS----IQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGI 406
            |||.|..::..|:.:    ||:.|.::...|..|.|..|:..::.|:||.||..|..|.:..|.|
Human    60 RNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDI 124

  Fly   407 VAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESL 471
            .|:|..:.:.|..||.|.|.:|.|:.|..|:..||..|.:|.|.||.
Human   125 WALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNS------------------ 171

  Fly   472 QMQENPLSCDCSIRPFAEWLQESQLHSSLSAS---CVTPPRLEGAPLLQVPVETLSCDMDNVEKD 533
                  |:|||.::...|||    .|::.:.:   |.:|||.:...:..:|:....|    :..|
Human   172 ------LNCDCKVKWLVEWL----AHTNTTVAPIYCASPPRFQEHKVQDLPLREFDC----ITTD 222

  Fly   534 NANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLILTWLLNLSKKDYMCDAIFVYKEEH 598
                ....:|||.|       .:|.|..|    :|:|        |.|:.......|..:.|.::
Human   223 ----FVLYQTLAFP-------AVSAEPFL----YSSD--------LYLALAQPGVSACTILKWDY 264

  Fly   599 INEILID------NSPIHCESKVVNGQNTVSVIVPDSSSLEIGESYRFCLVMIQEQKPDSELNIG 657
            :...|.|      .|.:||:..||:.|  :.|:|...    .|.||      |....|::
Human   265 VERQLRDYDRIPAPSAVHCKPMVVDSQ--LYVVVAQL----FGGSY------IYHWDPNT----- 312

  Fly   658 CSNITRLERSSP----------------------------GAVPVSRQYQR--------RPYYNA 686
             :..|||:...|                            ||..:.|.:|.        .|::..
Human   313 -TRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRD 376

  Fly   687 NEL-------KPEVVHDAGED----YQVNQRRFNSVVGSQPQQTQQSTLLHSYTVIDSLNKSFLP 740
            .:|       ||.::..:...    ||.::.:...|...:..|...:..:          |.|..
Human   377 TDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAV----------KHFRA 431

  Fly   741 G----LGLGVLVTSVLVLIWGATRIRQTGG--SSGG--------GGRNGDSIDSNSS 783
            |    |.|...:....:|.|..||..:...  |.|.        |||...::.|:.|
Human   432 GRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFS 488

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.