DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DMAP1 and dmap1

DIOPT Version :9

Sequence 1:	NP_611503.1	Gene:	DMAP1 / 37339	FlyBaseID:	FBgn0034537	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001005440.1	Gene:	dmap1 / 448027	XenbaseID:	XB-GENE-948170	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	447	Identity:	218/447 - (48%)
Similarity:	304/447 - (68%)	Gaps:	40/447 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ADVRDILDMERANTPEVT-----RDSFLATKKRNFERTKTAS-RRPEGMHREVFALLYTDKKDAP 61
            |||||||::...:: |||     :|...|.||::.:.::|.: :|||||||||:||||:||||||
Frog     5 ADVRDILELGGGDS-EVTGIINKKDIINADKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAP 68

  Fly    62 PLLPTDTALGIGAGYKETKARLGMKKVRKWEWAPFSNPARNDSAVFHHWKRVTDNSTDYPFAKFN 126
            ||||:||.    .||:..||:||.||||.|:|.||:||||.|.|:|.||:|.::...|||||:||
Frog    69 PLLPSDTT----QGYRTVKAKLGCKKVRPWKWMPFTNPARKDGAIFFHWRRASEEGKDYPFARFN 129

  Fly   127 KQLEVPSYTMTEYNAHLRNNINNWSKVQTDHLFDLARRFDLRFIVMADRWNRQQHGTKTVEELKE 191
            |.::||.|:..||..:|.:  :.|:|.:|||||||.|||||||||:.||::.||...::.|:||:
Frog   130 KSVQVPVYSEQEYQMYLHD--DGWTKAETDHLFDLCRRFDLRFIVIHDRYDHQQFKKRSAEDLKD 192

  Fly   192 RYYEVVALLAKAK-NQTSEKKVFVYDVEHERRRKEQLEKLFKRTTQQVEEENMLINEMKKIEARK 255
            |||.:.|.||..: ...::.|:.|:|..||||||||||:|:.||.:||.||..||.|::|||:||
Frog   193 RYYGICAKLANIRATPGTDMKIPVFDAGHERRRKEQLERLYNRTPEQVSEEEYLIQELRKIESRK 257

  Fly   256 KERERKTQDLQKLISQADQQNEHASNTPSTRKYEKKLHKKKVHQQPRPSRVDSVVNAIEIGSSGI 320
            ||||:|.|||||||:.||       .|...|:.|:|..|||:     |.:.::...|:. .::||
Frog   258 KEREKKAQDLQKLITAAD-------TTTELRRAERKATKKKL-----PQKKETEKPAVP-ETAGI 309

  Fly   321 KFADLRGSGVSLRSQRMKLPANIGQRKVKALEQAIQEFKVDPAPPPTEDICTSFNELRSDMVLLC 385
            :|.|.:.:||:|||||||||:::||:|:|||:|.:.|..||..|.|||:|...|||||||:|||.
Frog   310 RFPDFKSAGVTLRSQRMKLPSSVGQKKIKALDQMLTELGVDLNPMPTEEIVQMFNELRSDLVLLY 374

  Fly   386 ELRTALSTCVYEMESLKHQYEA-ACPGKTLNIPP------------SLVPIKTEALD 429
            ||:.|.|:|.||::.|:|::|| :..|.|..:.|            ....:|:||.|
Frog   375 ELKQAFSSCEYELQMLRHRFEALSKSGSTSTVLPGDGVAGESQAASGTEEVKSEAKD 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DMAP1	NP_611503.1	SANT_DAMP1_like	120..200	CDD:318509	42/79 (53%)
DMAP1	NP_611503.1	DMAP1	240..412	CDD:310242	84/172 (49%)
dmap1	NP_001005440.1	SANT_DAMP1_like	123..202	CDD:406645	42/80 (53%)
dmap1	NP_001005440.1	DMAP1	242..401	CDD:398903	84/171 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4147
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41311
Inparanoid	1	1.050	391	1.000	Inparanoid score	I1947
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D474387at33208
OrthoFinder	1	1.000	-	-		FOG0005191
OrthoInspector	1	1.000	-	-		oto103652
Panther	1	1.100	-	-	LDO	PTHR12855
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1419
SonicParanoid	1	1.000	-	-		X3704
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190