DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DMAP1 and Dmap1

DIOPT Version :9

Sequence 1:	NP_611503.1	Gene:	DMAP1 / 37339	FlyBaseID:	FBgn0034537	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001015006.1	Gene:	Dmap1 / 298447	RGDID:	1311295	Length:	468	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	213/434 - (49%)
Similarity:	301/434 - (69%)	Gaps:	28/434 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ADVRDILDM-----ERANTPEVTRDSFLATKKRNFERTKTAS-RRPEGMHREVFALLYTDKKDAP 61
            |||||||::     :.|:.....:|.....||::.:.::|.: :|||||||||:||||:||||||
  Rat     5 ADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAP 69

  Fly    62 PLLPTDTALGIGAGYKETKARLGMKKVRKWEWAPFSNPARNDSAVFHHWKRVTDNSTDYPFAKFN 126
            ||||:||    |.||:..||:||.||||.|:|.||:||||.|.|:|.||:|..:...|||||:||
  Rat    70 PLLPSDT----GQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFN 130

  Fly   127 KQLEVPSYTMTEYNAHLRNNINNWSKVQTDHLFDLARRFDLRFIVMADRWNRQQHGTKTVEELKE 191
            |.::||.|:..||..:|.::.  |:|.:|||||||:|||||||:|:.||::.||:..::||:|||
  Rat   131 KTVQVPVYSEQEYQLYLHDDA--WTKAETDHLFDLSRRFDLRFVVIHDRYDHQQYKKRSVEDLKE 193

  Fly   192 RYYEVVALLAKAKN-QTSEKKVFVYDVEHERRRKEQLEKLFKRTTQQVEEENMLINEMKKIEARK 255
            |||.:.|.||..:. ..::.|:.|:|..||||||||||:|:.||.:||.||..|:.|::||||||
  Rat   194 RYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARK 258

  Fly   256 KERERKTQDLQKLISQADQQNEHASNTPSTRKYEKKLHKKKVHQQPRPSRVDSVVNAIEIGSSGI 320
            ||||:::|||||||:.||       .|...|:.|:|..|||:     |.:.::...|:. .::||
  Rat   259 KEREKRSQDLQKLITAAD-------TTAEQRRTERKAPKKKL-----PQKKEAEKPAVP-ETAGI 310

  Fly   321 KFADLRGSGVSLRSQRMKLPANIGQRKVKALEQAIQEFKVDPAPPPTEDICTSFNELRSDMVLLC 385
            ||.|.:.:||:|||||||||:::||:|:|||||.:.|..|:.:|.|||::...|||||||:|||.
  Rat   311 KFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLY 375

  Fly   386 ELRTALSTCVYEMESLKHQYEAACPGKTLNIP--PSLVPIKTEA 427
            ||:.|.:.|.||::.|:|::||......|..|  |::.|....|
  Rat   376 ELKQACANCEYELQMLRHRHEALARAGVLGGPATPAVGPTPASA 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DMAP1	NP_611503.1	SANT_DAMP1_like	120..200	CDD:318509	43/79 (54%)
DMAP1	NP_611503.1	DMAP1	240..412	CDD:310242	82/171 (48%)
Dmap1	NP_001015006.1	SANT_DAMP1_like	124..203	CDD:406645	43/80 (54%)
Dmap1	NP_001015006.1	DMAP1	243..402	CDD:398903	82/171 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350918
Domainoid	1	1.000	155	1.000	Domainoid score	I4154
eggNOG	1	0.900	-	-		E1_KOG2656
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41311
Inparanoid	1	1.050	404	1.000	Inparanoid score	I1850
OMA	1	1.010	-	-		QHG59227
OrthoDB	1	1.010	-	-		D474387at33208
OrthoFinder	1	1.000	-	-		FOG0005191
OrthoInspector	1	1.000	-	-		oto96960
orthoMCL	1	0.900	-	-		OOG6_102680
Panther	1	1.100	-	-	LDO	PTHR12855
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3704
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770