DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DMAP1 and swc4

DIOPT Version :9

Sequence 1:	NP_611503.1	Gene:	DMAP1 / 37339	FlyBaseID:	FBgn0034537	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_593568.2	Gene:	swc4 / 2542412	PomBaseID:	SPAC9G1.13c	Length:	437	Species:	Schizosaccharomyces pombe

Alignment Length:	448	Identity:	128/448 - (28%)
Similarity:	204/448 - (45%)	Gaps:	87/448 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SADVRDILDMERANTPEVTRDSFLATKKRNFERTKT-ASRRPEGMHREVFALLYTDKKDAPPLLP 65
            |||:||:.::.   .||:          .|.:::|| ..|||||:.||:::||  .:..||
pombe     3 SADIRDVFELP---PPEI----------GNKQKSKTPTERRPEGISRELYSLL--GENSAP---- 48

  Fly    66 TDTALGIGAGYKETKARLGMKKVRKWEWAPFSNPARNDSAVFHHW--KRVTDNSTDYPFAKFNKQ 128
                |.|.....:.|.::. .|.:.|...|||..:|.|....|||  |...|:...|.|.|||..
pombe    49 ----LAIYQKKFKEKPKVS-HKAKNWVRQPFSISSRKDDFTLHHWVLKSEVDSEASYKFEKFNVP 108

  Fly   129 LEVPSYTMTEYNAHLRNNINNWSKVQTDHLFDLARRFDLRFIVMADRWNRQQHGT-KTVEELKER 192
            |.:..||..||..:|::  .:|:|.:||:||.|.:.:||||.|:|||::.:::.. :|:|:||:|
pombe   109 LFIIDYTDEEYQNYLKD--EDWNKDETDYLFRLCKDYDLRFFVIADRYDNEKYKKHRTLEDLKDR 171

  Fly   193 YYEVVALLAKAKN--------QTSEKKVFVYDVEHERRRKEQLEKLFKRTTQQVEEENMLINEMK 249
            :|.|...:..|:|        |:|......|:.|.|..||:.|..|..||.::|.||..|..|:|
pombe   172 FYSVSRKILLARNPINSMTAAQSSLLNTMEYNKEQEVIRKKYLIGLASRTPEEVAEEEALFIELK 236

  Fly   250 KIEARKKERERKTQDLQKLISQADQQNE----HASNTP-----------STRKYEKKLHKKKVHQ 299
            :||.   .:.:...|..:::...|:|..    |..:|.           ::::.:.|:.:..|..
pombe   237 RIET---SQAKLLSDRDEVLRLLDEQKGDGGIHEYHTSAGMSSLIQDMINSQRTKNKVEEAIVSS 298

  Fly   300 QPRPSRVDSVVNA-----------IEIGSS------GIKFADLRGSGVSLRSQRMKLPANIGQRK 347
            ....|.|.||:|.           |..|..      ||.:.:....|..:|||  |:||
pombe   299 SAPSSGVSSVLNTPTRPHALSTPRIRYGPQPTDPQFGITWHEKLHPGTFVRSQ--KIPA------ 355

  Fly   348 VKA-LEQAIQEFKVDPAPP-----PTEDICTSFNELRSDMVLLCELRTALSTCVYEME 399
            :|| |.|.:.....:....     ||......|.||::.:|.|.||:..:.....|.|
pombe   356 IKASLSQRVSSVMTELGVSSRLIMPTAKNFEKFVELQNSIVSLLELKRKVDRLSQETE 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DMAP1	NP_611503.1	SANT_DAMP1_like	120..200	CDD:318509	33/80 (41%)
DMAP1	NP_611503.1	DMAP1	240..412	CDD:310242	45/198 (23%)
swc4	NP_593568.2	SANT_DAMP1_like	101..179	CDD:292898	32/79 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	68	1.000	Domainoid score	I2729
eggNOG	1	0.900	-	-		E1_KOG2656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I1409
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005191
OrthoInspector	1	1.000	-	-		oto101184
orthoMCL	1	0.900	-	-		OOG6_102680
Panther	1	1.100	-	-	LDO	PTHR12855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1419
SonicParanoid	1	1.000	-	-		X3704
TreeFam	1	0.960	-	-
	12	11.850