DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment rig and WDR61

DIOPT Version :9

Sequence 1:NP_611499.3 Gene:rig / 37335 FlyBaseID:FBgn0250850 Length:1235 Species:Drosophila melanogaster
Sequence 2:NP_001290176.1 Gene:WDR61 / 80349 HGNCID:30300 Length:305 Species:Homo sapiens


Alignment Length:364 Identity:79/364 - (21%)
Similarity:126/364 - (34%) Gaps:149/364 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   458 IWNTNTGAHAGKNYSKSKTAGKLNNVY----WLNNHVIV--SLSRHQLFFWSVEFERKMLRYKIS 516
            ||:...|.:..:| |::...|.|:::.    |.:..:.:  ||..|||...||:....:   .|:
Human    19 IWSVAWGTNKKEN-SETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTL---PIA 79

  Fly   517 KDKSHSCHLQDIVSFACDSSKEMIWLCRNNRQIGMMNPKTGRMADFYGTVAFGVRAMAECPDDMN 581
            ...|...|::             :|...|.:||                               .
Human    80 ASSSLDAHIR-------------LWDLENGKQI-------------------------------K 100

  Fly   582 KIALGCSDRRVAFFDISKLTTSCLPIDSVYVSSNVYCLAWSPNCLELAFGTFDGTVGILDVERMK 646
            .|..|                   |:|:       :.||:||:...||.||..|.|.|..||   
Human   101 SIDAG-------------------PVDA-------WTLAFSPDSQYLATGTHVGKVNIFGVE--- 136

  Fly   647 VKTHLRTPHKKEVYSLVWQDHFIYFI-------------VNRVLGFFDLRKSKIEPTIVNCISRP 698
                   ..||| |||..:..||..|             ::.::..||:...|:..|:     ..
Human   137 -------SGKKE-YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTL-----EG 188

  Fly   699 SYLSIR------DSFLFV-GTDDGLLQIHERDSGMEKSWSPFIRQSAL------FARYVTDIAWC 750
            ..:.||      ||.|.| .:|||.::|::            ::.:.|      .|.:|.::|:|
Human   189 HAMPIRSLTFSPDSQLLVTASDDGYIKIYD------------VQHANLAGTLSGHASWVLNVAFC 241

  Fly   751 PLDSNKFAVSGNDRSVYVMEFQPTERNWKT-----LHTF 784
            | |...|..|.:|:||.|         |..     :|||
Human   242 P-DDTHFVSSSSDKSVKV---------WDVGTRTCVHTF 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rigNP_611499.3 WD40 <80..>215 CDD:295369
WD40 80..>215 CDD:225201
WD40 repeat 116..160 CDD:293791
WD40 repeat 167..204 CDD:293791
WD40 434..821 CDD:225201 79/364 (22%)
WD40 446..719 CDD:295369 61/286 (21%)
WD40 613..874 CDD:295369 53/203 (26%)
WD40 repeat 617..654 CDD:293791 13/36 (36%)
WD40 repeat 659..691 CDD:293791 9/44 (20%)
WD40 repeat 693..732 CDD:293791 10/45 (22%)
WD40 repeat 744..785 CDD:293791 15/46 (33%)
WD40 repeat 793..831 CDD:293791
WD40 repeat 838..861 CDD:293791
WDR61NP_001290176.1 WD40 13..302 CDD:238121 79/364 (22%)
WD 1 14..57 8/38 (21%)
WD40 repeat 19..62 CDD:293791 10/43 (23%)
WD 2 62..101 12/85 (14%)
WD40 repeat 68..105 CDD:293791 10/83 (12%)
WD 3 104..143 19/75 (25%)
WD40 repeat 110..146 CDD:293791 19/46 (41%)
WD 4 146..187 7/45 (16%)
WD40 repeat 152..188 CDD:293791 5/40 (13%)
WD 5 188..227 11/50 (22%)
WD40 repeat 193..229 CDD:293791 11/47 (23%)
WD 6 230..269 13/48 (27%)
WD40 repeat 236..271 CDD:293791 14/45 (31%)
WD 7 272..305
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4155
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.