DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rig and CG1523

DIOPT Version :9

Sequence 1:	NP_611499.3	Gene:	rig / 37335	FlyBaseID:	FBgn0250850	Length:	1235	Species:	Drosophila melanogaster
Sequence 2:	NP_651635.2	Gene:	CG1523 / 43400	FlyBaseID:	FBgn0039601	Length:	621	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	85/420 - (20%)
Similarity:	148/420 - (35%)	Gaps:	116/420 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   745 TDIAWCP--LDSNKFAVSGNDRSVYVMEFQPTERNWKTLH---TFTANTEKASITSMRWSHTQKH 804
            ||...|.  .|...||...:|.:|.:.:.:..::..:.||   .:..|.|.:|         :..
  Fly    91 TDSVNCIKFFDERLFATGSDDFTVALWDLRNMKQKLRVLHGHSNWVKNIEYSS---------KDK 146

  Fly   805 LLLTFHIEGKVCLWNCNAPEKPPLTI--TYHCP--MWCGMFLPTNENIIMCS--GKALSVELIDI 863
            ||::...:|.:..|:.|:..:..|..  .:|..  |.| ...||.:.:::|:  |..:.:..:|:
  Fly   147 LLVSSGFDGSIFTWDINSQTEQGLISQRVFHASGLMRC-RISPTGDKLVLCTSGGYIMIIHHLDL 210

  Fly   864 KDALEGDEKSIC---PKVDALLNVKWASKSLTQPYAPVLTAAEKKRQRRDQRKAAAKLEVDVANK 925
            ...    .|.:|   |.:..|:       .|.:.|.|                .|||.: .|.:|
  Fly   211 TTL----HKDLCGFRPGIYRLM-------QLGEQYIP----------------QAAKYD-HVFSK 247

  Fly   926 DQKKIQESVTAVIDNPTNDKCTQETPVEEMLEALSLDKE-----QNNRSAKECPKCKEQSPDSFT 985
            .|||  ..|..|.|.|.|:..       ||:.||.:...     ..|.|      |.|||
  Fly   248 RQKK--NRVELVTDFPENNDA-------EMIMALQIHPHCCCMLTRNVS------CDEQS----- 292

  Fly   986 HSRTCLYLTQKELNKSALEKLAIVLTEDSAKIDKSVLISKLFSSKVMAKELIATELTNLKHSNTK 1050
             ..||::...:|..:|..|:      ::.....|...:|...:|:           ::|..|..:
  Fly   293 -EWTCIHDINEEPVRSEDEQ------DEVEPQPKRKRVSTTLASR-----------SSLNESQDQ 339

  Fly  1051 DIAPLCLAMSTFKLRE------ELEQHIANKTLTERHVSLAPSVSF--TLWQDCCRAYAKQMEEK 1107
            |...|....:...||.      :|:...|.:..::....|..|.||  .:|     |....::|:
  Fly   340 DTVGLTPRQARRPLRVSSVQVFQLDNSGAGRGASDNPSVLTRSDSFIPDIW-----AAEVTVQER 399

  Fly  1108 GYIM--------HAATYLFSQGMQSEAIKL 1129
            ....        |.:.|.|...:.|..:.|
  Fly   400 AIRQNRARVSNNHVSGYNFVYAISSGVLPL 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rig	NP_611499.3	WD40	<80..>215	CDD:295369
		WD40	80..>215	CDD:225201
		WD40 repeat	116..160	CDD:293791
		WD40 repeat	167..204	CDD:293791
		WD40	434..821	CDD:225201	17/80 (21%)
		WD40	446..719	CDD:295369
		WD40	613..874	CDD:295369	28/139 (20%)
		WD40 repeat	617..654	CDD:293791
		WD40 repeat	659..691	CDD:293791
		WD40 repeat	693..732	CDD:293791
		WD40 repeat	744..785	CDD:293791	10/44 (23%)
		WD40 repeat	793..831	CDD:293791	6/39 (15%)
		WD40 repeat	838..861	CDD:293791	5/24 (21%)
CG1523	NP_651635.2	WD40	43..235	CDD:295369	32/164 (20%)
		WD40	<45..>218	CDD:225201	28/140 (20%)
		WD40 repeat	51..87	CDD:293791
		WD40 repeat	95..129	CDD:293791	6/33 (18%)
		WD40 repeat	136..174	CDD:293791	9/46 (20%)
		WD40 repeat	181..210	CDD:293791	6/29 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4155
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900