DRSC/TRiP Functional Genomics Resources

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Protein Alignment rig and wdr32

DIOPT Version :10

Sequence 1:NP_611499.3 Gene:rig / 37335 FlyBaseID:FBgn0250850 Length:1235 Species:Drosophila melanogaster
Sequence 2:NP_998111.2 Gene:wdr32 / 405882 ZFINID:ZDB-GENE-040426-2314 Length:508 Species:Danio rerio


Alignment Length:608 Identity:107/608 - (17%)
Similarity:185/608 - (30%) Gaps:251/608 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   408 ASGTPQTKSEPQSNL-------------------QVVPAISAETISLTSV-NSTHLETLLVSIDG 452
            :||.|....||:::|                   ...||....|...... .|:..|   |:.||
Zfish     2 SSGHPSDNEEPRADLLREEEEEEEEEEDSDEDRGSTRPASPQATRECAGTQGSSRPE---VTADG 63

  Fly   453 DEVMMIWNTNTGAHAGKNYSKSKTAGKLNNVY-WLNNHVI-----VSLSRHQLFFWSVEFERKML 511
                     .||:.:|   |..:.:|..:::: |:....|     |..:|...        |.|.
Zfish    64 ---------GTGSASG---SGCRGSGACDSLFSWICRRKIRRGPYVDPARDHF--------RTMT 108

  Fly   512 R-YKISKDKSHSCHLQ----------------DIVSFACDSSKEMIWLCRNNRQIGMMNPKTGRM 559
            | |......:.|.:|.                .:::.||:.::.:::...::|.|..:       
Zfish   109 RLYSSMSPAADSVNLSTQTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPVSSRHIKTL------- 166

  Fly   560 ADFYGTVAFGVRAMAECPDDM----NKIALGCS-DRRVAFFDISKLTTSCLPIDSVYVSSNVYCL 619
                      |.|..:|.:::    |::...|| |..:|.:|:.||.:....:..  .:|.|..:
Zfish   167 ----------VEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNSKVCSLHG--HASWVKNI 219

  Fly   620 AWSPNCLELAFGTFDGTVGILDVERMKVKTHLRTPHKKEVYSLVWQDHFIYFIVNRVLGFFDLR- 683
            .:..:...|....|||.|...|..|.   |....||||                     ||..| 
Zfish   220 EYDTHTRLLVTSGFDGNVITWDTNRF---TEDGCPHKK---------------------FFHTRY 260

  Fly   684 --KSKIEPTIVNCISRPSYLSIRDSFLFVGTDDG-LLQIHERDSGMEKSWSPFIRQSALFARYVT 745
              :.::.|   :|           |.:.:.|..| ||.:|:.|          :.||.....|..
Zfish   261 LMRMRLTP---DC-----------SKMLISTSSGYLLILHDLD----------LTQSLEVGSYRI 301

  Fly   746 DIAWCPLDSNKFAVSGN-------------------------------------DRSVYVMEFQP 773
            ..|..|..|.:.:.:|:                                     ||...:...|.
Zfish   302 LRARRPPLSTEGSSAGSRSGGPRHTIDNKNHPHREGLSPRNSLEVLTPEIPGERDRGNCITSLQL 366

  Fly   774 TERNWKTLHTFTANTEKASITSMRWSHTQKHLLLTFHIEGKVCLWNC------NAPEKPP----- 827
            ..:.|.||...::|.:...                         |.|      .||.:||     
Zfish   367 HPKGWATLLRCSSNMDDQE-------------------------WTCVYEFQEGAPPRPPVSPRC 406

  Fly   828 -LTITYH--------------CPMWCGMFLPTNENIIMCSGKALSV----------ELID---IK 864
             |.:|::              |      |.|  :..::||.....|          ||:|   ::
Zfish   407 SLRLTHYIEEANVGRGYIKELC------FSP--DGRLICSPYGYGVRLLAFDENCAELVDCMPVR 463

  Fly   865 DALEGDEKSICPKVDALLNVKWA 887
            .|...:.:||....|.:|..|::
Zfish   464 TAQLREVRSIYSHSDVVLTSKFS 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rigNP_611499.3 WD40 repeat 116..160 CDD:293791
WD40 repeat 167..204 CDD:293791
WD40 446..719 CDD:475233 57/304 (19%)
WD40 613..874 CDD:475233 58/340 (17%)
WD40 repeat 617..654 CDD:293791 8/36 (22%)
WD40 repeat 659..691 CDD:293791 4/34 (12%)
WD40 repeat 693..732 CDD:293791 8/39 (21%)
WD40 repeat 744..785 CDD:293791 10/77 (13%)
WD40 repeat 793..831 CDD:293791 7/49 (14%)
WD40 repeat 838..861 CDD:293791 6/32 (19%)
wdr32NP_998111.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..75 18/87 (21%)
WD 1 126..165 4/38 (11%)
WD40 <128..>294 CDD:441893 42/232 (18%)
WD40 repeat 132..167 CDD:293791 4/51 (8%)
WD 2 169..207 10/37 (27%)
WD40 repeat 174..210 CDD:293791 8/35 (23%)
WD 3 211..250 10/43 (23%)
WD40 repeat 216..242 CDD:293791 6/25 (24%)
WD 4 256..295 13/62 (21%)
WD40 repeat 261..288 CDD:293791 8/40 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 307..343 3/35 (9%)
WD 5 356..396 9/64 (14%)
WD 6 419..457 7/45 (16%)
WD 7 475..508 3/12 (25%)
Blue background indicates that the domain is not in the aligned region.

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