Protein Alignment rig and Rbcn-3B

DIOPT Version :10

• Sequence 1: NP_611499.3
• Gene: rig / 37335
• FlyBaseID: FBgn0250850
• Length: 1235
• Species: Drosophila melanogaster
• Sequence 2: XP_061518785.1
• Gene: Rbcn-3B / 3291629
• VectorBaseID: AGAMI1_004638
• Length: 1473
• Species: Anopheles gambiae
• Alignment Length: 1351
• Identity: 234/1351 - (17%)
• Similarity: 411/1351 - (30%)
• Gaps: 471/1351 - (34%)

  Fly    15 GNVSLAAAAPDGGLLYAGIRCI--------------------NYISAPPANGEQPQVVTMSTRIN 59
            |.:.|....||  .|....||:                    |::.:...|||      |.|
Mosquito    41 GQICLWQVDPD--TLQMTPRCLLVGHTAPVLCLTRASIIQDNNFLVSSSENGE------MCT--- 94

  Fly    60 ILALDVSPMWGLGNGGPTKPFAIVGDDLSVQVWDCALGEAVIGHKAHQHQHEARDVRVVHHTTNS 124
                     |.|.:|..|:...:.....::|.:               |.....|:|:
Mosquito    95 ---------WDLVDGKCTESIKMPQVHTNIQAY---------------HMANCDDIRL------- 128

  Fly   125 VLMSYLANG---NILSMDASDL-VIYCVASNTYCRRSTFISPRNHQLTMVRCSPYNDNLFAVGTA 185
                 ..||   .|:.||...| |::|::|..   ...:||    .|.::|.|...|::....|.
Mosquito   129 -----FCNGYYAEIMVMDPFSLEVLFCLSSKV---NPDWIS----ALHVLRPSKRKDDVVLAITT 181

  Fly   186 MGNVLVCDLR------------------------KMNIVYKFHGHKAPICGLAWREVPAAE-DEK 225
            .|.|.|..|.                        .||...:.......:|...|:...|.: ...
Mosquito   182 TGTVKVWTLLGNENKYSEPIYENESKQIRCLNAITMNCCSQNQRTVLIVCAKYWQIYDAGDFTVL 246

  Fly   226 TNNLALSAEEWRSRNGGQEEKPKTKPPPLTKSKAAESDDPFDIYNFDHLEYEFGAPIAERRRKSS 290
            .:.::.|.|.|.   ||.                ..|:|...:::.:...|.|..|  ......:
Mosquito   247 CSVISPSGERWM---GGD----------------FLSNDRVILWSDEGKGYLFRLP--ANSIPDN 290

  Fly   291 EDCGGEFVGLEKPAGAAVLDFVEACESVKAELLASRQEDKTQHVEVTLHDCEPTKPTGPLSDAST 355
            :|..|..||.:.|....:|                     :|..|..| .|.||.
Mosquito   291 KDFHGPSVGKDTPFLYCIL---------------------SQTGEKPL-SCPPTM---------- 323

  Fly   356 ISNKNDASDSTEGSLEVIQYSSSSDDAVIVDGEAAKPKREVLHHIYHQAEVHASGTPQTKSEPQS 420
                                      .::....:.|.::.:|               :..||...
Mosquito   324 --------------------------KLVTSNRSGKTQKYLL---------------RGDSEGYV 347

  Fly   421 NLQVVPAISAETISLTSVNSTH---LETLLVSIDGDEVMMIWNTNTGAHAG---KNYSKSKTAGK 479
            |:..||.||.|.|........|   ||:.:.:    .::..||.......|   :.|..|:...|
Mosquito   348 NIWAVPDISMEQIKQIQTQKQHPASLESTICT----SLLEAWNKMNPLPVGILDQLYQNSEPMIK 408

  Fly   480 LNNVYWLNNHVIVSLSRHQLFFWSVEFERKMLRYKISKDKSHSCHLQDIVSFACDSSKEMIWLCR 544
            |....:|.....:.:.|                    :|.|       |:......:..:..|..
Mosquito   409 LTASIYLPQQSRLVVGR--------------------EDGS-------IIIVPATQTVMLHLLHG 446

  Fly   545 NNRQIG------MMNPKTGRMADFYGTVAFGVRAMAECPD------DMNKIALGCSDRRVAFFDI 597
            |::|..      ::|..:||           |..:. ||.      |.:.:..|..|..|..:|:
Mosquito   447 NHQQFSDWPPHQILNGHSGR-----------VNCLL-CPSLAHSRYDKSHLVSGGVDFAVCLWDL 499

  Fly   598 ---SKLTTSCLPIDSVYVSSNVYCLAWSPNCLE-----LAFGTFDGTVGILDVERMKVKTHLRTP 654
               |.:...|     |:.......|...|.|..     :.....|.:|.:|.::..|..| |.:.
Mosquito   500 YSGSLIHRFC-----VHAGEITQLLVPPPTCSPRILKCICSVASDHSVTLLSLQERKCVT-LASR 558

  Fly   655 HKKEVYSLVWQDHFIYFIVNRVLGFFDLRKSKIEPTIVNCISRPSYLSIRDSFLFVGTDDGLLQI 719
            |...|.|:.|                                ||     .|.||.||..||.:.:
Mosquito   559 HLFPVISIKW--------------------------------RP-----LDDFLIVGCSDGTVYV 586

  Fly   720 HERDSG-MEKSWSPFIRQSALFARYVTDIAWCPLDSNKFAVSGND-------------------R 764
            .:.::| :::.....:.:..|.|        |..:|.:...|...                   |
Mosquito   587 WQMETGHLDRVLHGILAEEVLNA--------CDENSGETGSSTGSTSEMGLANPAVHFFRGLRHR 643

  Fly   765 SVYVMEFQPTERNWKTLHTFTANTEKAS------------ITSMRWS--HTQKHLLLTFHIEGKV 815
            ::..:. ..|:|....|....|:..:..            |..:|.:  ..:.|:|. |.|||
Mosquito   644 NINAIR-HATQRGIHQLQQLHAHNNQHGDFLMKNRSSPLIIQGLRTNPKDAESHILF-FDIEG-- 704

  Fly   816 CLWNCNAPE---KPPLTITYHCPMWCGMFLPT-NENIIMCSGKALSVELIDIKDALEGDEKSICP 876
            .::..:|.|   ..|.|:...     |:.:|| .::....:||.:|.....:|:. .||.:.|..
Mosquito   705 LIFELHAEEYAAMSPNTLEAE-----GLLIPTGTDSHASDAGKKISDFFGRVKNK-AGDMEKILK 763

  Fly   877 KVD---ALLNVKWASKSLTQPYAPVLTAAEKKRQRRDQRKAAAKLEVDVAN-----KDQKKIQES 933
            :.|   .|..:|..::::                   |.|..||||..|.|     ||...|.:.
Mosquito   764 EKDKHGILAKMKEGAENV-------------------QTKVQAKLESVVKNVGETGKDSSDITKK 809

  Fly   934 VTAVIDNPTNDKCTQETPVEEMLEAL----SLDKEQNNRSAKECPKCKEQSPDSF------THSR 988
            :...::      .|....|.::|.:|    .||...:.....:....:...|.||      .:..
Mosquito   810 IAPRME------ATHVMEVAQLLLSLIHSWGLDPHLDKVCETQLGLLRPMIPVSFGVLSKGGYMS 868

  Fly   989 TCLYLTQKE--LNKSALEKLAIVLTEDSAKIDKSVLISKLFSSKVMAKELIATELTN------LK 1045
            ..|...|..  :|.:|.|.....:|.:..:.:.   ::|||::::..:  ::|.||:      :.
Mosquito   869 LLLPTWQNNIVINSTADELKTAAMTPEQFRQEG---LTKLFTARLHWE--LSTTLTSNHLLAMVA 928

  Fly  1046 HSNTKDIAPLCLAMSTFKLREELEQHIANKTLTERHVSLAPSVSFTLW---QDCCRAYAKQMEE- 1106
            .|||.    :.:.|:|| :.|:           ||...|....:...|   ::...|:.:|..:
Mosquito   929 MSNTL----MSMNMATF-IPEQ-----------ERARKLHRQSTRATWSNEEEQEEAFTQQQAQI 977

  Fly  1107 -KGYIMHAATYLFSQGMQSEAIKLFLANEYYKEALVHARICLPATDPLIKTVINNWLEHLEGTGN 1170
             :|:.:.:..:.|   :..|.|....||.:.:              |.::.:...|..|......
Mosquito   978 KQGWSLLSTHHCF---LLPEKIDALDANNFKR--------------PQVEMMARRWQHHCLEIRE 1025

  Fly  1171 FAAAALICVLDNEMLRG--------YSYLRKYRNCTPEIADLMDQIKRIGQ 1213
            .|...|:..|.....:|        ..||..|.:..|    ::.|....||
Mosquito  1026 AAQQLLLGELGRMGKKGRKQLVESWAQYLPMYTHTEP----IVQQAPATGQ 1072

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rig	NP_611499.3	WD40 repeat	116..160	CDD:293791	10/47 (21%)
		WD40 repeat	167..204	CDD:293791	11/60 (18%)
		WD40	446..719	CDD:475233	51/295 (17%)
		WD40	613..874	CDD:475233	54/303 (18%)
		WD40 repeat	617..654	CDD:293791	9/41 (22%)
		WD40 repeat	659..691	CDD:293791	3/31 (10%)
		WD40 repeat	693..732	CDD:293791	10/39 (26%)
		WD40 repeat	744..785	CDD:293791	7/59 (12%)
		WD40 repeat	793..831	CDD:293791	12/42 (29%)
		WD40 repeat	838..861	CDD:293791	6/23 (26%)
Rbcn-3B	XP_061518785.1	None