| Sequence 1: | NP_611499.3 | Gene: | rig / 37335 | FlyBaseID: | FBgn0250850 | Length: | 1235 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_863651.1 | Gene: | APAF1 / 317 | HGNCID: | 576 | Length: | 1248 | Species: | Homo sapiens |
| Alignment Length: | 834 | Identity: | 144/834 - (17%) |
|---|---|---|---|
| Similarity: | 242/834 - (29%) | Gaps: | 380/834 - (45%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 86 DLSVQVWDCALGEAVIGHKAHQHQHEARDVRVVHHTTNSVLMSYLANGNILSMDASDLVIYCVAS 150
Fly 151 N-TYCRRSTF--ISPRNHQLTMVRCSPYNDNLFAVGTAMGNVLVCDLRKMNIVYKFHGHKAPICG 212
Fly 213 LAWREVPAAEDEKTNNLALSAEEWRSRNGGQEEKPKTKPPPLTKSKAAESDDPFDIYNFDHLEYE 277
Fly 278 FGAPIAERRRKSSEDCGGEFVGLEKPAGAAVLDFVEACESVKAELLASRQEDKTQHVEVTLHDCE 342
Fly 343 PTKPTGPLSDASTISNKNDASDSTEGSLEVIQYSSSSDDAVIVDGEAAKPKREVLHHIYHQAEVH 407
Fly 408 ASG-----------TPQ-TKSEPQSNLQVVPAISAETISLTSVNSTHLETLLVSIDGDEVMMIWN 460
Fly 461 TNTGAHAGKNYSKSKTAGKLNNVYWLN--------NHVIVSLSRHQLFFWSVEFERKMLRYKISK 517
Fly 518 DKSHSCHLQDIVSFACDSSKEMIWLCRNNRQIGMMNPKTGRMADFYGTVAFGVRAMAECPDDMNK 582
Fly 583 IALGCSDRRVAFFDISKLTTSCLPIDSVYVSSNVYCLAWSPNCLELAFGTFDGTVGILDVERMKV 647
Fly 648 KTHLRTPHKKEVYSLVWQDHFIYFIVNRVLGFFDLRKSKIEPTIVN----------------CI- 695
Fly 696 ------SRPSYLSIRDSFLFVGTDDGLLQIHERDSG-MEKSWSPFIRQSALFARYVTDIAWCPL- 752
Fly 753 -DSNKFAVSGNDRSVYVMEFQ---PTERNWKTLHTFTANTEKASITSMRWSHTQKHLLLTFHIEG 813
Fly 814 KVCLWNCNAPEK----PPLT----------ITYHCPMWCGMFLPTNENIIMCSG 853 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| rig | NP_611499.3 | WD40 | <80..>215 | CDD:295369 | 29/131 (22%) |
| WD40 | 80..>215 | CDD:225201 | 29/131 (22%) | ||
| WD40 repeat | 116..160 | CDD:293791 | 10/46 (22%) | ||
| WD40 repeat | 167..204 | CDD:293791 | 9/36 (25%) | ||
| WD40 | 434..821 | CDD:225201 | 68/423 (16%) | ||
| WD40 | 446..719 | CDD:295369 | 47/303 (16%) | ||
| WD40 | 613..874 | CDD:295369 | 54/284 (19%) | ||
| WD40 repeat | 617..654 | CDD:293791 | 10/36 (28%) | ||
| WD40 repeat | 659..691 | CDD:293791 | 4/31 (13%) | ||
| WD40 repeat | 693..732 | CDD:293791 | 9/62 (15%) | ||
| WD40 repeat | 744..785 | CDD:293791 | 9/45 (20%) | ||
| WD40 repeat | 793..831 | CDD:293791 | 10/51 (20%) | ||
| WD40 repeat | 838..861 | CDD:293791 | 4/16 (25%) | ||
| APAF1 | NP_863651.1 | CARD_APAF1 | 7..92 | CDD:260034 | |
| NB-ARC | 129..374 | CDD:395745 | |||
| APAF1_C | 453..587 | CDD:407760 | |||
| WD40 | 607..910 | CDD:238121 | 77/439 (18%) | ||
| WD 1-1 | 613..652 | ||||
| WD40 repeat | 623..655 | CDD:293791 | |||
| WD 1-2 | 655..694 | 6/20 (30%) | |||
| WD40 repeat | 660..697 | CDD:293791 | 7/23 (30%) | ||
| WD 1-3 | 697..738 | 10/47 (21%) | |||
| WD40 repeat | 703..741 | CDD:293791 | 9/44 (20%) | ||
| WD 1-4 | 741..780 | 15/79 (19%) | |||
| WD40 repeat | 746..791 | CDD:293791 | 19/137 (14%) | ||
| WD 1-5 | 796..836 | 16/86 (19%) | |||
| WD40 repeat | 802..870 | CDD:293791 | 25/134 (19%) | ||
| WD 1-6 | 838..877 | 16/71 (23%) | |||
| WD 1-7 | 880..910 | 2/29 (7%) | |||
| WD40 repeat | 885..939 | CDD:293791 | 7/63 (11%) | ||
| Interpropeller linker. /evidence=ECO:0000250 | 910..921 | 2/20 (10%) | |||
| WD 2-1 | 922..958 | 8/73 (11%) | |||
| WD 2-2 | 959..998 | 12/50 (24%) | |||
| WD40 | 961..1234 | CDD:238121 | 54/284 (19%) | ||
| WD40 repeat | 964..990 | CDD:293791 | 10/25 (40%) | ||
| WD 2-3 | 1001..1040 | 10/58 (17%) | |||
| WD40 repeat | 1006..1030 | CDD:293791 | 5/39 (13%) | ||
| WD 2-4 | 1042..1080 | 6/37 (16%) | |||
| WD40 repeat | 1047..1082 | CDD:293791 | 7/44 (16%) | ||
| WD 2-5 | 1083..1122 | 8/45 (18%) | |||
| WD40 repeat | 1089..1124 | CDD:293791 | 9/41 (22%) | ||
| WD 2-6 | 1125..1164 | 8/41 (20%) | |||
| WD40 repeat | 1130..1172 | CDD:293791 | 10/44 (23%) | ||
| WD 2-7 | 1175..1212 | 6/29 (21%) | |||
| WD40 repeat | 1180..1213 | CDD:293791 | 6/24 (25%) | ||
| WD 2-8 | 1213..1248 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4155 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||