Protein Alignment CG13436 and CFAP206

DIOPT Version :10

• Sequence 1: NP_611498.1
• Gene: CG13436 / 37334
• FlyBaseID: FBgn0034532
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001026913.1
• Gene: CFAP206 / 154313
• HGNCID: 21405
• Length: 622
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 140/615 - (22%)
• Similarity: 248/615 - (40%)
• Gaps: 138/615 - (22%)

  Fly    25 VDKEFVIYMVHLLARDRRKG------LLKYDLNKPTACAIEGFVNTIVDSYVNSKDCTMANMKMA 83
            |.:..:.:||..:..|...|      |:|.|        ::..|...:...:::|:.::..:||.
Human    28 VSETLIAFMVKAVVLDPSNGFNMDRTLMKSD--------VQNLVKLCMTRLLDTKNPSLDTIKMQ 84

  Fly    84 WVMKKGVTIDLEYVKK-----KYEEKFQTELQLLIKDILQYPETCSKVQLDQLFAKMQVFIVACY 143
                  |..|:.|..:     ::....::.|..:.::|.. ...|:|.:|:.|:.|:..:::...
Human    85 ------VYFDMNYTNRVEFLEEHHRVLESRLGSVTREITD-NRACAKEELESLYRKIISYVLLRS 142

  Fly   144 SLGSPKNHVLLKLTAQALNSVIGRSDLQNYVLKKKYHRLEYLQRLSATVGGIVIYNND-GPDGDR 207
            .||||.:...::....||.||..:::|..::...|..:...|:.|:..|.||.::|.| |..|:.
Human   143 GLGSPTDIKTVREVTAALQSVFPQAELGTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEG 207

  Fly   208 ENVRSVVDDLEMAQKNTEAAFAASMGRAVKMQSTCQAALDDLINIDHKDET-----LTYRVPLEH 267
                  :|||.....             |.:.:|.|       :||::.||     ..|...||.
Human   208 ------IDDLPAVLH-------------VAIPATMQ-------HIDYQLETARSQVYRYTAILEK 246

  Fly   268 L--DRLNQFAATYFMLHRCLTTLNEHYQKTVYL-------------IEVEHKRYQCVICKIDDTL 317
            .  |.|.:.....:||...|..:.::   .|:|             :|:..|:....:.::..|:
Human   247 AANDPLMRAELQPYMLKEALYNIRQY---EVFLQIILSDIITGAQEVEMMTKQLGAHLEQLKMTI 308

  Fly   318 SMRTAIDSELIFPHFVYLSQVW----------GNLNNYLNHIVELNKLREQVEALVVDDLMT--L 370
            ..:.|:.:..:||.|:.||.:|          |.|:|...||   .......|....:.:|.  |
Human   309 KSKIAVPTSQVFPIFIALSTLWTSLQDETIVVGVLSNLFTHI---QPFLGAHELYFPERVMQCHL 370

  Fly   371 TKATIAELQALHKRIKKPKVCSFEERM-DAV-----KEL-----QTDGNFCKLNKADIKEFCSLA 424
            ..||:           |..||..:|.| |.|     ::|     :|..||.|| ....:.||:..
Human   371 NGATV-----------KTDVCRMKEHMEDRVNVADFRKLEWLFPETTANFDKL-LIQYRGFCAYT 423

  Fly   425 MTITNGLLMPAQVTRKLCSNVD--ITFGFRDPRYARFAELRFEPFIAAFRKVVFNNANLALLFKL 487
            ...|:|||:|......:....:  .||..:|..|: ||| ..|.:|...|:....|..|..|.:|
Human   424 FAATDGLLLPGNPAIGILKYKEKYYTFNSKDAAYS-FAE-NPEHYIDIVREKAKKNTELIQLLEL 486

  Fly   488 DDALIEQELQNLV------------VEPPKQTDFECQTEMVVTNDLTPANWINVTWNAWDYHRET 540
                 .|:.:..:            ::|..:.:...||.   |:.|.|....:..||.|:..|:.
Human   487 -----HQQFETFIPYSQMRDADKHYIKPITKCESSTQTN---THILPPTIVRSYEWNEWELRRKA 543

  Fly   541 IHLANIRKKQTNDAQTNISYGRRNAQNQTY 570
            |.|||:|:|.|:..||::|:.||...:|.|
Human   544 IKLANLRQKVTHSVQTDLSHLRRENCSQVY 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13436	NP_611498.1	FAP206	216..492	CDD:463432	73/320 (23%)
CFAP206	NP_001026913.1	FAP206	214..491	CDD:463432	72/321 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	570..592		2/4 (50%)