Protein Alignment FAM21 and RCSD1

DIOPT Version :10

• Sequence 1: NP_611496.1
• Gene: FAM21 / 37331
• FlyBaseID: FBgn0034529
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: NP_443094.3
• Gene: RCSD1 / 92241
• HGNCID: 28310
• Length: 416
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 109/508 - (21%)
• Similarity: 161/508 - (31%)
• Gaps: 168/508 - (33%)

  Fly   968 PPEDNDHAGEEVQKEAEPQKDELASTTRIHTIFYDDFSETARAGAVQPAPK---RFP------FD 1023
            |.|.|    ..|...|.|...:||..          |.|.|.|....||.|   |.|      |
Human     5 PAETN----ANVDNSASPSVAQLAGR----------FREQAAAAKETPASKPTRRKPPCSLPLF- 54

  Fly  1024 DEPPPADETDRSEVKETPELQKP------TSPVKKLKMPNININVHALLPGSG------------ 1070
              ||..|.....|.|..|....|      :||:.:....|:..:..|||||:.
Human    55 --PPKVDLGQNGEEKSPPNASHPPKFKVKSSPLIEKLQANLTFDPAALLPGASPKSPGLKAMVSP 117

  Fly  1071 -----SVPKLIRKQESSSSERDEPQAT--VQTEAEAPSSGQNTVSSADGVLQHVNKSRARGPAKR 1128
                 |.|       ||...|..|...  |....:.|..|.:        |...||.|.||..||
Human   118 FHSPPSTP-------SSPGVRSRPSEAEEVPVSFDQPPEGSH--------LPCYNKVRTRGSIKR 167

  Fly  1129 RPSTRRGRKENYAKSLLDAGQNEGPTASTRDSPEVEHSERSSIKAPSPQYVKPEKLFSTPAQQIQ 1193
            ||.:||     :.:|..|.|:       ..|...||.|:::..|......|.|.| ...|...:.
Human   168 RPPSRR-----FRRSQSDCGE-------LGDFRAVESSQQNGAKEEDGDEVLPSK-SKAPGSPLS 219

  Fly  1194 PQ------------LQRPP----PSNTGGSFLDSPDEDDSFFNSVPTKTVEGKQG---------- 1232
            .:            .::||    ||.|     :..:||.:        |.|.|.|
Human   220 SEGAAGEGVRTLGPAEKPPLRRSPSRT-----EKQEEDRA--------TEEAKNGEKARRSSEEV 271

  Fly  1233 -------TDPPKSYRSFLDSPDADDKLFSDLENNKAGINVVPVEK----KPPKMANSFLASPDED 1286
                   .:.|:|.::  ..|:|:::..|..|...|| ....:||    |..::.|..: .|:.|
Human   272 DGQHPAQEEVPESPQT--SGPEAENRCGSPREEKPAG-EEAEMEKATEVKGERVQNEEV-GPEHD 332

  Fly  1287 DFLFDSVKTNATTTAQKAFAAEIMNAFQKVTTAPPKPSNAKEAAKPKSQAAPKLFDDSDDDDDDL 1351
                          :|:....|...|.::...:|  |...|....||.:
Human   333 --------------SQETKKLEEGAAVKETPHSP--PGGVKGGDVPKQE---------------- 365

  Fly  1352 FARAPSIQTASKPVQAKQPPKPAATSLFSSDDEEAEVPVKSAPAKKLPVKPSK 1404
              :....|.....::....|:.....|.:|.:.::| |....|....||:.:|
Human   366 --KGKEKQQEGAVLEPGCSPQTGPAQLETSSEVQSE-PAVPKPEDDTPVQDTK 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAM21	NP_611496.1	PHA03307	353..>583	CDD:223039
		PHA03307	931..>1207	CDD:223039	71/288 (25%)
		CAP-ZIP_m	1045..1163	CDD:464595	34/142 (24%)
RCSD1	NP_443094.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..84		25/95 (26%)
		CAP-ZIP_m	81..>166	CDD:464595	23/99 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..416		81/398 (20%)
		RCSD	229..329	CDD:428350	23/116 (20%)