Protein Alignment CG11180 and GPATCH8

DIOPT Version :9

• Sequence 1: NP_611495.1
• Gene: CG11180 / 37330
• FlyBaseID: FBgn0034528
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_011522859.1
• Gene: GPATCH8 / 23131
• HGNCID: 29066
• Length: 1531
• Species: Homo sapiens
• Alignment Length: 807
• Identity: 169/807 - (20%)
• Similarity: 261/807 - (32%)
• Gaps: 271/807 - (33%)

  Fly    25 DENRFGTKMLEKMGWTKGSGLGANLNGEKDFVRIRFKNDAEGLGFEQRDDQWTVHEDGFNGLLKS 89
            :.:..|.::|:|.||..|.|||.:|.|..|.:.|..|.|..|:|..:.:..:.  ||.
Human    39 ESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYA--EDA------- 94

  Fly    90 LNGEDSGGIDKEPESEEEARPMGFGFKAIEPEEPSKKKLKENTSGMSLEERSKQSRARVHYKKFT 154
              .|....::.|.|..||.|.....:  ::.|:...|.|::..:....|...||.:....:....
Human    95 --TERRRVLEVEKEDTEELRQKYKDY--VDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHI 155

  Fly   155 RGKDLALYSEKDLANIFGKKATEDVERYPEPVLAVQPEEPNPNFAGVQTI--------------V 205
            ...|.|...|          .|:|   |.|..:.....:.||:..|.|..              |
Human   156 NSYDHAHKQE----------GTQD---YYESEIIADVLKANPSNLGAQITRRLKDLKQREFARNV 207

  Fly   206 TGLSTTDYFKQKMEAMKNRL----------------------------KKGSQVEDNNEAQTN-- 240
            :..|..|  ::|.|....||                            ::|.: :|.:|:.||
Human   208 SSRSRKD--EKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGE-DDKDESATNSG 269

  Fly   241 -------GHAEKFEQISADND------EVT----------------------------------- 257
                   |...:|   |.|..      ::|
Human   270 TGATASCGLGSEF---STDKGGPFTAVQITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSF 331

  Fly   258 --SKKKKKK--------KD--KERADEPPTKEEEPEQVASMPKKKKKSKRSSLDEEKLVESEERT 310
              :||...|        ||  :|...|..||.:|......:.|.......|:||.:|       .
Human   332 SFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKK-------E 389

  Fly   311 DEQPTAVEEIEQDAPKLKKKKKSKGSSLDEIEQSENNFVEEKLVKSKE--------RTSEQPTAV 367
            ||.|.....:.....|||:.|:.:|:...|.|.  .:::.....|.|.        |.|||....
Human   390 DEDPQDGGSLASTLSKLKRMKREEGAGATEPEY--YHYIPPAHCKVKPNFPFLLFMRASEQMDGD 452

  Fly   368 EEIE-QDVPKLKK----KKKS--KRSSVDETEKTDNNCVEMAEITEESERTSSKKKKSKKEEESA 425
            .... ::.|:.||    |.||  |.::....|||.:   |::|..:|:..|...:..||.|.:.|
Human   453 NTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVS---EVSEQPKETSMTEPSEPGSKAEAKKA 514

  Fly   426 ---EVSIQTEESDQKKKRKSD--KNKEIAEDSIEEPAAKKKKKSKK-----------SDEVIVID 474
               :||.|:.||..:|..::.  ::....|.|:..||.|:.::..|           .||...:.
Human   515 LGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQ 579

  Fly   475 ------------------------DDDLHRNNESHTSNENRTK------------------NKSK 497
                                    |..|.||.::.|....:.|                  ||||
Human   580 WPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSK 644

  Fly   498 -------------------------SKDSQETTQIQEEITIDLTAEAPS------------KKKK 525
                                     ..:.||........|.|.....||            ||||
Human   645 EVGGEKIVRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKK 709

  Fly   526 KSKEEKRKDNDEKDLEETPPASEATEK----KSKKKSKLKSSA----EPSTKLEITSFALAVEAA 582
            ..|..|.|...:.|.||....:|:.||    |.:|:.|.||||    |...|.|...   :...|
Human   710 HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG---SGSPA 771

  Fly   583 VDNRKDTGGED--RNDVSADKNNSGNK 607
            ...|:....:|  |..:.|::.:||.|
Human   772 PPRRRRRAQDDSQRRSLPAEEGSSGKK 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11180	NP_611495.1	G-patch	27..70	CDD:279867	17/42 (40%)
GPATCH8	XP_011522859.1	G-patch	40..82	CDD:279867	16/41 (39%)
		zf-C2H2_jaz	136..163	CDD:288983	5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I5047
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050