DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9945 and RPN14

DIOPT Version :9

Sequence 1:NP_611494.1 Gene:CG9945 / 37329 FlyBaseID:FBgn0034527 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_011511.3 Gene:RPN14 / 852880 SGDID:S000002972 Length:417 Species:Saccharomyces cerevisiae


Alignment Length:377 Identity:72/377 - (19%)
Similarity:133/377 - (35%) Gaps:118/377 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 IMPVNGGEDDCQWIDV----NGLPSHRLAIFSLRYSPTGDKIIGGSNNSTVIVTDIRTRNT-QIL 259
            ::..|...||..:|:|    |.:..|::.            ::|.|..     .|....|| :.:
Yeast    17 VLEENDENDDEFYINVDKNLNEIKEHKIV------------VLGNSRG-----VDAGKGNTFEKV 64

  Fly   260 RTH----RMPGKD--VNSVC-----FLHDKDPNVI----------IAGCDDGLLKVYDLRTTFRS 303
            .:|    |:.|.|  .|::.     .|...|...:          |.|..:|.:||.|.....: 
Yeast    65 GSHLYKARLDGHDFLFNTIIRDGSKMLKRADYTAVDTAKLQMRRFILGTTEGDIKVLDSNFNLQ- 128

  Fly   304 RDLSKSVASFIGHYDGITYIDSRNDGYHVLSNSKDQSIKIWDIRQPSNMR--------------- 353
            |::.::      |...||.:.....|..::|:|:|..:|||.::..||.|               
Yeast   129 REIDQA------HVSEITKLKFFPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAII 187

  Fly   354 NRSRS--RQQVDPT--TWDYRWNRVPREFYNPHKPLEGDSSIMTYRG-----HRVT--------- 400
            :|.|:  ...:|.|  .|:.........|.....|.:|.:||..:.|     |.::         
Yeast   188 DRGRNVLSASLDGTIRLWECGTGTTIHTFNRKENPHDGVNSIALFVGTDRQLHEISTSKKNNLEF 252

  Fly   401 -------------------------KTL-LRAKFS------PMEQTGQRYIYTGCATGRIIIYDV 433
                                     :|: |.:||:      .::.....|||.|...|.:..:|:
Yeast   253 GTYGKYVIAGHVSGVITVHNVFSKEQTIQLPSKFTCSCNSLTVDGNNANYIYAGYENGMLAQWDL 317

  Fly   434 LTGK--IQEAIEGHRTVIRDLDWHPDRSEIVSGSWDTHVHLNNFSRSNANRP 483
            .:.:  :.|.:....|.|.:: :....:..||..:||.:.|:..|...:.||
Yeast   318 RSPECPVGEFLINEGTPINNV-YFAAGALFVSSGFDTSIKLDIISDPESERP 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9945NP_611494.1 WD40 128..467 CDD:295369 66/359 (18%)
WD40 repeat 131..170 CDD:293791
WD40 <133..478 CDD:225201 70/370 (19%)
WD40 repeat 178..220 CDD:293791 6/23 (26%)
WD40 repeat 225..260 CDD:293791 5/35 (14%)
WD40 repeat 270..314 CDD:293791 10/58 (17%)
WD40 repeat 323..395 CDD:293791 20/90 (22%)
WD40 repeat 403..443 CDD:293791 10/48 (21%)
RPN14NP_011511.3 WD40 repeat 96..133 CDD:293791 7/37 (19%)
WD40 133..>357 CDD:421866 42/230 (18%)
WD40 repeat 140..176 CDD:293791 11/35 (31%)
WD40 repeat 181..217 CDD:293791 5/35 (14%)
WD40 repeat 227..283 CDD:293791 5/55 (9%)
WD40 repeat 290..328 CDD:293791 7/37 (19%)
WD40 repeat 335..378 CDD:293791 9/35 (26%)
WD40 repeat 385..412 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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