DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9945 and AT4G03020

DIOPT Version :9

Sequence 1:	NP_611494.1	Gene:	CG9945 / 37329	FlyBaseID:	FBgn0034527	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001190666.1	Gene:	AT4G03020 / 828111	AraportID:	AT4G03020	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	159/512 - (31%)
Similarity:	260/512 - (50%)	Gaps:	67/512 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DFDSSDNELGFNVINFTVNAMDLRSDYCSSEMPVI---------RGKPDLVKFQKTDMYKEIQAS 71
            :||:  :|:|     :.::.:::.||.|.:...|.         |....|     .|:..||...
plant     7 EFDA--DEMG-----YAMSRLEIESDLCDTGKDVCGVGSSSGSHRSSEHL-----ADLDHEISQV 59

  Fly    72 SGLVSNPNNRW------------NLVHALQQRENGLASPHSASFSKNQQRYISNLYIPNKKATRL 124
            :.|.|:|:.|:            :.|..|..||:..:.  ...||.....::.:.|:|.|....:
plant    60 TKLKSSPHQRYSREVPGRHQLPVSTVRMLAGRESNFSG--RGRFSAADCCHMLSRYLPTKGPWLV 122

  Fly   125 MSLESKIFVTKFNRSGSKLLTACQDGFVRIYDGAKGTYHLLNRIRARDVEWSIIDADFSPNGEHF 189
            ..::|:.:|::|:..||..:...|...:|||:..|| :.:...|.|:.:.|::.|...||:..:.
plant   123 DQMDSRAYVSQFSTDGSLFIAGFQGSRIRIYNVEKG-WKVQKDILAKSLRWTVTDTSLSPDQRNL 186

  Fly   190 AYSTWSRSLFIMPVNGG--EDDCQWIDV-NGLP-------SHRLAIFSLRYSPTGDKIIGGSNNS 244
            .|::.|..:.|:.|..|  |......:: :||.       .:...|||:::|..|.:::.||::.
plant   187 VYASMSPIVHIVDVGSGSTESHANVTEIHDGLDFSSDEDGGYSFGIFSVKFSTDGREVVAGSSDD 251

  Fly   245 TVIVTDIRTRNTQILRT--HRMPGKDVNSVCFLHDKDPNVIIAGCDDGLLKVYDLRTTFRSRDLS 307
            ::.|.|:.. |...|||  |.   .|||:|||. |:..|:|::|.||.|.||:| |..|..||
plant   252 SIYVYDLEA-NRVSLRTVAHT---SDVNTVCFA-DESGNLILSGSDDNLCKVWD-RRCFIGRD-- 308

  Fly   308 KSVASFIGHYDGITYIDSRNDGYHVLSNSKDQSIKIWDIRQPSNMRNRSRSRQQV-DPTTWDYRW 371
            |.....:||.:|:|:||||.||.:.:||.|||:||:||||:   |.:.:.:|.:| ....|||||
plant   309 KPAGVLVGHLEGVTFIDSRGDGRYFISNGKDQTIKLWDIRK---MSSSAPARHEVLRNYEWDYRW 370

  Fly   372 NRVPREFYNPHKPLEGDSSIMTYRGHRVTKTLLRAKFSPMEQTGQRYIYTGCATGRIIIYDVLTG 436
            ...|.|..:...||  |.|:.||:||.|.:||:|..|||...|||:|||||.....:.|||:::|
plant   371 MDYPTEARDLKHPL--DQSVSTYKGHSVLRTLIRCYFSPAHSTGQKYIYTGSNDSSVYIYDLVSG 433

  Fly   437 KIQEAIEGHRTVIRDLDWHPDRSEIVSGSWDTHVHLNNFSRSN-----ANRPVKRSH 488
            .....::.|.:.:||.:|||....::|.|||..:....|..|.     :.:.|:|.|
plant   434 DKVAVLKHHSSPVRDCNWHPYYPTLISSSWDGDLVKWEFPGSGEAPIMSKKRVRRRH 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9945	NP_611494.1	WD40	128..467	CDD:295369	126/351 (36%)
		WD40 repeat	131..170	CDD:293791	11/38 (29%)
		WD40	<133..478	CDD:225201	128/357 (36%)
		WD40 repeat	178..220	CDD:293791	11/51 (22%)
		WD40 repeat	225..260	CDD:293791	10/34 (29%)
		WD40 repeat	270..314	CDD:293791	19/43 (44%)
		WD40 repeat	323..395	CDD:293791	32/72 (44%)
		WD40 repeat	403..443	CDD:293791	17/39 (44%)
AT4G03020	NP_001190666.1	WD40 repeat	130..169	CDD:293791	12/39 (31%)
		WD40	133..465	CDD:421866	125/345 (36%)
		WD40 repeat	175..227	CDD:293791	11/51 (22%)
		WD40 repeat	232..268	CDD:293791	12/36 (33%)
		WD40 repeat	275..319	CDD:293791	21/47 (45%)
		WD40 repeat	324..392	CDD:293791	32/72 (44%)
		WD40 repeat	400..430	CDD:293791	15/29 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I4019
eggNOG	1	0.900	-	-		E1_KOG0266
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I1160
OMA	1	1.010	-	-		QHG58362
OrthoDB	1	1.010	-	-		D1219799at2759
OrthoFinder	1	1.000	-	-		FOG0006573
OrthoInspector	1	1.000	-	-		oto3563
orthoMCL	1	0.900	-	-		OOG6_104227
Panther	1	1.100	-	-	LDO	PTHR19847
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4812
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840