Protein Alignment Hil and mical2b

DIOPT Version :9

• Sequence 1: NP_611493.2
• Gene: Hil / 37328
• FlyBaseID: FBgn0050147
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_005174396.1
• Gene: mical2b / 569564
• ZFINID: ZDB-GENE-061207-15
• Length: 1679
• Species: Danio rerio
• Alignment Length: 535
• Identity: 114/535 - (21%)
• Similarity: 191/535 - (35%)
• Gaps: 140/535 - (26%)

  Fly    10 TCLRCSETVYQVDRVGPLKDFTFFHSGCFKCVHCGTKLTLKTYFNNQHKQDDKE--VYCSSHVP- 71
            ||:.|.:.||.::|:.  .:..|||..||:|..||..|.|     ..|..|.::  .||..|..
Zfish  1012 TCVFCQKRVYIMERLS--AEGFFFHRECFRCHICGCSLRL-----GAHTFDSQQGTFYCKMHFSQ 1069

  Fly    72 -KSGPGHL--DQTSVGIRQA----LNAPRTNKFVNEQIRGTRSEVDGGPLGGSR----QSTPNGY 125
             |:...|.  :....|||.:    .|...|:        |||.:..||....|.    |:.|:
Zfish  1070 RKTSTRHRRGEIQDGGIRSSSITISNHTSTD--------GTRGQPSGGEFDSSTQQDLQTLPD-- 1124

  Fly   126 GSREISSPSQ-NDSDYKYGRFDASALHIAHALKQTEIQKAYNKAREKPIDFYLAREEQAHLEMKH 189
             |:||.|.|: .||..|....|:     |.|...:.:||.....         |:.|..:..:..
Zfish  1125 -SKEIISVSEVKDSSKKADPADS-----APACPDSPLQKVKRST---------AKGEITNKNILW 1174

  Fly   190 RKEEDD-----LYRKFASKRAEEDRKI--QDEFQDEWERELQRLTHKFEKELATSRR---SRDEA 244
            :|:...     |.:||...:.|:..::  :::...::|...:.|:.|.....:|...   ::|
Zfish  1175 KKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKD-- 1237

  Fly   245 NILTMRHEQQKEDLEKNMTLRRSKK----------------------KESITRKMLEHERYETAA 287
            |..|...|..|..|.:...|....|                      |:.:|..:.|.|:.....
Zfish  1238 NSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWD 1302

  Fly   288 LV--------DRQSSEMLELISARRSE----YMQSE---SIF--------LDDEFSEGAVPVEYP 329
            |.        ::|...:...||.:...    :.|.|   .:|        |...||:|:.||...
Zfish  1303 LTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLR 1367

  Fly   330 LNAPIPAPP-AVSKFQIYTDPIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFR 393
            .|.|:.|.| :...|.:   ...|:|.:|..            .||.:...|..|:.|.| ::..
Zfish  1368 RNRPMKARPLSEGSFNV---GAVFQDEERCG------------SLVDEGEARPRTESEIA-SLLE 1416

  Fly   394 WITVKNLNAMHFDDDLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGY-QP 457
            .:.:.:..:....||:....|                  ::|..::.|....::|..:|.|. |.
Zfish  1417 QVALGSKTSRGTKDDMASLPP------------------RKLNFFSSLRIKRVEGAEQSRGEGQK 1463

  Fly   458 GVKFQDSRFRNSWNA 472
            .:....|||||..:|
Zfish  1464 DILSILSRFRNKASA 1478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hil	NP_611493.2	LIM_Ltd-1	11..70	CDD:188827	19/60 (32%)
		BAR	<147..>265	CDD:299863	21/127 (17%)
		TGc	418..486	CDD:214673	12/56 (21%)
mical2b	XP_005174396.1	FAD_binding_3	86..>274	CDD:332373
		CH	522..623	CDD:306753
		LIM_Mical	1013..1067	CDD:188823	19/60 (32%)
		Atrophin-1	1080..>1344	CDD:331285	55/290 (19%)
		YesN	<1308..1371	CDD:330857	13/62 (21%)
		DUF3585	1530..1665	CDD:314926

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810